70833-07-7
70833-07-7 structure
- Name: Prifuroline
- Chemical Name: prifuroline
- CAS Number: 70833-07-7
- Molecular Formula: C14H16N2O
- Molecular Weight: 228.29000
- Catalog: Research Areas Cardiovascular Disease
- Create Date: 2018-06-19 22:13:04
- Modify Date: 2024-01-08 15:51:20
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Prifuroline is an antiarrhythmic agent.
| Name | prifuroline |
|---|
| Description | Prifuroline is an antiarrhythmic agent. |
|---|---|
| Related Catalog | |
| In Vivo | Prifuroline is an antiarrhythmic agent. Prifuroline dose-dependently antagonizes the arrhythmogenic action of aconitine in rats, when administered either intravenously (5, 10 or 20 mg/kg) or intraduodenally (10, 20 or 50 mg/kg). Prifuroline also diminishes ventricular susceptibility to electrical stimulation in open-chest rats. The arrhythmias induced in dogs by coronary artery ligation are markedly antagonized by Prifuroline after doses of 5 and 10 mg/kg i.v. or 30 mg/kg intraduodenally. The duration of its antiarrhythmic activity in this model of arrhythmias in conscious dogs is much longer after intraduodenal than after i.v. administration[1]. |
| References |
| Density | 1.18g/cm3 |
|---|---|
| Boiling Point | 383.8ºC at 760 mmHg |
| Molecular Formula | C14H16N2O |
| Molecular Weight | 228.29000 |
| Flash Point | 185.9ºC |
| Exact Mass | 228.12600 |
| PSA | 28.74000 |
| LogP | 2.31580 |
| Index of Refraction | 1.617 |
| Storage condition | 2-8℃ |