2555-28-4

2555-28-4 structure

Name: 7-Methoxy-4-methylcoumarin
Chemical Name: 7-Methoxy-4-methylcoumarin
CAS Number: 2555-28-4
Molecular Formula: C₁₁H₁₀O₃
Molecular Weight: 190.195
Catalog: Pharmaceutical intermediate Heterocyclic compound Pyran compound
Create Date: 2018-05-24 08:00:00
Modify Date: 2024-01-02 15:54:25
4-Methylherniarin (7-Methoxy-4-methylcoumarin) is a coumarin derivative and fluorescent label, has an antimicrobial activitiy against both gram positive and gram negative bacterial stains. 4-Methylherniarin displays good activity against B. subtilis and S.sonnei with IC50 values of 11.76 μg/ml and 13.47 μg/ml[1].

Name	7-Methoxy-4-methylcoumarin
Synonyms	METHYL-7-METHOXYCOUMARIN,4 Herniarin,4-methyl 4-methyl-7-methyloxycoumarin 4-METHYL-7-METHOXYCOUMARIN 7-Methoxy-4-methylcoumarin Coumarin,7-methoxy-4-methyl Methyl 4-methylumbelliferyl ether T66 BOVJ E1 IO1 4-methyl-7-methoxy-2H-1-benzopyran-2-one 7-Methoxy-4-methyl-2H-chromen-2-on 7-Methoxy-4-methylchromen-2-one 7-Methoxy-4-Methylcourmain 7-Methoxy-4-methyl-2H-1-benzopyran-2-one 2H-1-Benzopyran-2-one, 7-methoxy-4-methyl- 4-Methylherniarin 7-Methoxy-4-Methylcoumarine 7-methoxy-4-methyl-chromen-2-one 7-Methoxy-4-methyl-2H-chromen-2-one MFCD00009773 Hymechrome methyl ether

Description	4-Methylherniarin (7-Methoxy-4-methylcoumarin) is a coumarin derivative and fluorescent label, has an antimicrobial activitiy against both gram positive and gram negative bacterial stains. 4-Methylherniarin displays good activity against B. subtilis and S.sonnei with IC50 values of 11.76 μg/ml and 13.47 μg/ml[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
Target	IC50: 11.76 μg/ml (B. subtilis); 13.47 μg/ml (S.sonnei)[1]
References	[1]. Fauzia Anjum Chattha, et al. Potential antibacterial activity of coumarin and coumarin-3-acetic acid derivatives

Density	1.2±0.1 g/cm3
Boiling Point	340.1±37.0 °C at 760 mmHg
Melting Point	158-160 °C(lit.)
Molecular Formula	C₁₁H₁₀O₃
Molecular Weight	190.195
Flash Point	140.8±21.1 °C
Exact Mass	190.062988
PSA	39.44000
LogP	2.37
Vapour Pressure	0.0±0.7 mmHg at 25°C
Index of Refraction	1.556
Stability	Moisture, Temperature Sensitive
Water Solubility	DMF: soluble