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2277-92-1

2277-92-1 structure
2277-92-1 structure
  • Name: Oxyclozanide
  • Chemical Name: Oxyclozanide
  • CAS Number: 2277-92-1
  • Molecular Formula: C13H6Cl5NO3
  • Molecular Weight: 401.457
  • Catalog: analytical chemistry Standard Analytical standard
  • Create Date: 2018-03-01 08:00:00
  • Modify Date: 2024-01-02 18:24:48
  • Oxyclozanide is a salicylanilide anthelmintic drug that mainly acts by uncoupling oxidative phosphorylation in flukes.
Name Oxyclozanide
Synonyms 2,3,5-Trichlor-N-(3,5-dichlor-2-hydroxyphenyl)-6-hydroxybenzolcarboxamid
MFCD00864507
Zanilox
Oxyclozanide
diplin
3,3',5,5',6-Pentachloro-2'-hydroxysalicylanilid
EINECS 218-904-0
OXYCLOZAMIDE
Oxycloxanide
zanil
Saucylanilide
Benzamide, 2,3,5-trichloro-N-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxy-
3,3',5,5',6-pentachloro-2'-hydroxysalicylanilide
2,3,5-Trichloro-N-(3,5-dichloro-2-hydroxyphenyl)-6-hydroxybenzamide
oxyclozanid
Description Oxyclozanide is a salicylanilide anthelmintic drug that mainly acts by uncoupling oxidative phosphorylation in flukes.
Related Catalog
Target

Parasite[1]

References

[1]. Gokbulut C, et al. Comparative pharmacokinetics of levamisole-oxyclozanide combination in sheep and goats following per os administration. Can J Vet Res. 2014 Oct;78(4):316-20.
Density 1.8±0.1 g/cm3
Boiling Point 446.0±45.0 °C at 760 mmHg
Melting Point 205 - 210ºC
Molecular Formula C13H6Cl5NO3
Molecular Weight 401.457
Flash Point 223.5±28.7 °C
Exact Mass 398.879028
PSA 69.56000
LogP 8.67
Vapour Pressure 0.0±1.1 mmHg at 25°C
Index of Refraction 1.722
Storage condition 0-6°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :
CV8576000
CHEMICAL NAME :
Benzanilide, 2,2'-dihydroxy-3,3',5,5',6-pentachloro-
CAS REGISTRY NUMBER :
2277-92-1
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C13-H6-Cl5-N-O3
MOLECULAR WEIGHT :
401.45
WISWESSER LINE NOTATION :
QR BG DG FMVR BQ CG EG FG

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NATUAS Nature. (Nature Subscription Dept., POB 1018, Manasguan, NJ 08736) V.1- 1869- Volume(issue)/page/year: 210,744,1966
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - domestic
DOSE/DURATION :
60 mg/kg
TOXIC EFFECTS :
Behavioral - muscle weakness Gastrointestinal - hypermotility, diarrhea Nutritional and Gross Metabolic - weight loss or decreased weight gain
REFERENCE :
VETRAX Veterinary Record. (7 Mansfield St., London W1M 0AT, UK) V.1- 1888- Volume(issue)/page/year: 78,267,1966
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Mammal - cattle
DOSE/DURATION :
60 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold Behavioral - coma Lungs, Thorax, or Respiration - respiratory stimulation
REFERENCE :
VETRAX Veterinary Record. (7 Mansfield St., London W1M 0AT, UK) V.1- 1888- Volume(issue)/page/year: 78,267,1966
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Mammal - domestic
DOSE/DURATION :
10 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
VETRAX Veterinary Record. (7 Mansfield St., London W1M 0AT, UK) V.1- 1888- Volume(issue)/page/year: 78,267,1966
Symbol GHS07 GHS09
GHS07, GHS09
Signal Word Warning
Hazard Statements H302-H410
Precautionary Statements P273-P501
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn:Harmful;N:Dangerousfortheenvironment;
Risk Phrases R22;R50/53
Safety Phrases S60-S61
RIDADR UN 3077
RTECS CV8576000
HS Code 2924299090
HS Code 2924299090
Summary 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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title: CAS No. 2277-92-1 | Chemsrc address: https://m.chemsrc.com/en/baike/826628.html

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