104809-16-7

104809-16-7 structure
104809-16-7 structure
  • Name: 7-Methylguanosine 5'-diphosphate sodium
  • Chemical Name: 7-methyl-7,8-dihydroguanosine-5'-diphosphate
  • CAS Number: 104809-16-7
  • Molecular Formula: C11H19N5O11P2
  • Molecular Weight: 459.24300
  • Catalog: Research Areas Others
  • Create Date: 2016-03-01 08:01:18
  • Modify Date: 2024-01-02 21:08:44
  • 7-Methylguanosine 5'-diphosphate (7-Methyl-GDP) sodium, a cap analog, can be used in the synthesis of mRNA cap analogues[1].

Name 7-methyl-7,8-dihydroguanosine-5'-diphosphate
Synonyms MFCD00057869
Description 7-Methylguanosine 5'-diphosphate (7-Methyl-GDP) sodium, a cap analog, can be used in the synthesis of mRNA cap analogues[1].
Related Catalog
Target

Human Endogenous Metabolite

In Vitro 7-Methylguanosine 5'-diphosphate sodium inhibits binding of eukaryotic initiation factors to reovirus capped mRNA and complex formation involving uncapped mRNA or 18 S rRNA[1]. T. brucei mRNA decapping enzyme (TbDcp2) that cleaves 7-Methylguanosine 5'-diphosphate sodium from capped RNA to generate pRNA, a substrate for TbCe1[2].
References

[1]. Sonenberg N, et al. Nonspecific effect of m7GMP on protein-RNA interactions. J Biol Chem. 1978;253(19):6630-6632.

[2]. Ignatochkina AV, et al. The messenger RNA decapping and recapping pathway in Trypanosoma. Proc Natl Acad Sci U S A. 2015;112(22):6967-6972.

Molecular Formula C11H19N5O11P2
Molecular Weight 459.24300
Exact Mass 459.05600
PSA 260.85000
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