284474-82-4

284474-82-4 structure
284474-82-4 structure
  • Name: Tetramethyl-ammonium Bromide-d12
  • Chemical Name: tetrakis(trideuteriomethyl)azanium,bromide
  • CAS Number: 284474-82-4
  • Molecular Formula: C4BrD12N
  • Molecular Weight: 166.12300
  • Catalog: Research Areas Others
  • Create Date: 2018-09-05 17:29:06
  • Modify Date: 2024-01-01 19:37:08
  • Tetramethyl-ammonium Bromide-d12 is the deuterium labeled TMAB[1].

Name tetrakis(trideuteriomethyl)azanium,bromide
Synonyms Tetramethyl-d12-ammonium bromide
Description Tetramethyl-ammonium Bromide-d12 is the deuterium labeled TMAB[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216.  

Melting Point >300ºC
Molecular Formula C4BrD12N
Molecular Weight 166.12300
Exact Mass 165.09100
Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301-H315-H319-H335
Precautionary Statements P261-P301 + P310-P305 + P351 + P338
Personal Protective Equipment Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
Hazard Codes T: Toxic;
Risk Phrases 25-36/37/38
Safety Phrases 26-45
RIDADR UN 2811 6.1/PG 2