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107452-89-1

107452-89-1 structure
107452-89-1 structure
  • Name: ω-Conotoxin MVIIA
  • Chemical Name: Ziconotide acetate
  • CAS Number: 107452-89-1
  • Molecular Formula: C102H172N36O32S7
  • Molecular Weight: 2639.134
  • Catalog: Biochemical Peptide
  • Create Date: 2018-07-03 06:46:22
  • Modify Date: 2024-01-09 08:00:04
  • Ziconotide is an analgesic agent and has been used to treat neuropathic and non-neuropathic pain. Ziconotide acts by binding to N-type calcium channels situated on the terminal part of primary afferent neurons of the nociceptive pathway therefore reducing synaptic transmission with potent antinociceptive effects[1].

Name Ziconotide acetate
Synonyms Ziconotide
ω-conotoxin MVIIA
SNX-111,Ziconotide
o-Conotoxin MVIIA
SNX-111 Ziconotide
snx111
Ziconotideacetate
Prialt
SNX-111
CKGKGAKCSRLMYDCCTGSCRSGKC-NH2
Description Ziconotide is an analgesic agent and has been used to treat neuropathic and non-neuropathic pain. Ziconotide acts by binding to N-type calcium channels situated on the terminal part of primary afferent neurons of the nociceptive pathway therefore reducing synaptic transmission with potent antinociceptive effects[1].
Target

N-Type Ca2+ Channel

References

[1]. Brinzeu A, et al. Ziconotide for spinal cord injury-related pain. Eur J Pain. 2019 Oct;23(9):1688-1700.

Density 1.6±0.1 g/cm3
Molecular Formula C102H172N36O32S7
Molecular Weight 2639.134
Exact Mass 2637.098389
PSA 1310.94000
LogP -17.05
Index of Refraction 1.710
Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301 + H331
Precautionary Statements P261-P304 + P340 + P312-P403 + P233
Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T+
RIDADR UN 3172
WGK Germany 3
Packaging Group III
Hazard Class 6.1(b)