Name | 4-[(7-chloro-2-methoxy-1,5-dihydrobenzo[b][1,5]naphthyridin-10-yl)imino]-2,6-bis(pyrrolidin-1-ylmethyl)cyclohexa-2,5-dien-1-one,phosphoric acid |
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Synonyms |
Pyronaridine phosphate
Phenol,4-((7-chloro-2-methoxybenzo(b)-1,5-naphthyridin-10-yl)amino)-2,6-bis(1-pyrrolidinylmethyl)-,phosphate (1:4) Pyronaridine Tetraphosphate UNII-2T289F9ACO 4-[(7-Chloro-2-methoxybenzo[b][1,5]naphthyridin-10-yl)amino]-2,6-bis(1-pyrrolidinylmethyl)phenol phosphate (1:4) Phenol, 4-[(7-chloro-2-methoxybenzo[b]-1,5-naphthyridin-10-yl)amino]-2,6-bis(1-pyrrolidinylmethyl)-, phosphate (1:4) (salt) Pyranoridine phosphate |
Description | Pyronaridine tetraphosphate is a Mannich base anti-malarial with demonstrated efficacy against drug resistant Plasmodium falciparum, P. vivax, P. ovale and P. malariae. |
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Related Catalog | |
References |
Density | 1.357g/cm3 |
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Boiling Point | 657.2ºC at 760 mmHg |
Melting Point | 233-236° (dec) |
Molecular Formula | C29H44ClN5O18P4 |
Molecular Weight | 910.030 |
Flash Point | 351.3ºC |
Exact Mass | 909.132019 |
PSA | 424.03000 |
LogP | 2.32020 |
Index of Refraction | 1.72 |
Storage condition | 2-8°C |
Water Solubility | acetic acid: soluble5mg/mL |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
MUTATION DATA
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Symbol |
GHS07, GHS08 |
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Signal Word | Warning |
Hazard Statements | H302-H361 |
Precautionary Statements | P280-P301 + P312 + P330 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Faceshields;Gloves |
Hazard Codes | Xn |
Risk Phrases | 63-22-41 |
Safety Phrases | 26-36/37-39 |
RIDADR | NONH for all modes of transport |
RTECS | SK4920000 |