Henan Tianfu Chemical Co., Ltd.
China
Product Name: [(2R,5S)-5-(4-amino-2-oxopyrimidin-1-yl)-1,3-oxathiolan-2-yl]methyl 2-hydroxybenzoate
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Purity: 99.0%
Stocking Period: Inquiry
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Email: info@tianfuchem.com

173522-96-8

173522-96-8 structure

Name: Lamivudine salicylate
Chemical Name: [(2R,5S)-5-(4-amino-2-oxopyrimidin-1-yl)-1,3-oxathiolan-2-yl]methyl 2-hydroxybenzoate
CAS Number: 173522-96-8
Molecular Formula: C₁₅H₁₇N₃O₆S
Molecular Weight: 367.377
Catalog: Signaling Pathways Anti-infection HBV
Create Date: 2018-05-29 08:00:00
Modify Date: 2026-07-19 18:35:19
Lamivudine (BCH-189) salicylate is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Lamivudine salicylate can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS[1][2].

Name	[(2R,5S)-5-(4-amino-2-oxopyrimidin-1-yl)-1,3-oxathiolan-2-yl]methyl 2-hydroxybenzoate
Synonyms	(2r-cis)-4-amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1h)-pyrimidinone 2-hydroxybenzoate 2-Hydroxybenzoic acid - 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone (1:1) 2r-(Hydroxymethyl)-5(S)-Cytosin-1-Yl-1,3-Oxathiolanesalicycic Acid Salt Benzoic acid, 2-hydroxy-, compd. with 4-amino-1-[(2R,5S)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]-2(1H)-pyrimidinone (1:1) lamivudine salicylate 2R-(HYDROXYMETHYL)-5(S)-CYTOSIN-1-YL-1,3-OXATHIOLANESALICYCIC ACID SALT (LAMIVUDINE SALICYLATE) ((2R,5S)-5-(4-Amino-2-oxopyriMidin-1(2H)-yl)-1,3-oxathiolan-2-yl)Methyl 2-hydroxybenzoate 2R-(hydroxymethyl)-5(s)-cytosin-1-yl-[1,3]-oxathiolane salicylic acid salt (intermediate of lamivudine) (2R,5S)-4-Amino-1-[2-(hydroxymethyl)-1,3-oxathiolan-5-yl]- 2-(1H)-pyrimidinone salicylate(Lamivudine Salicylate) 2R-(hydroxymethyl)-5(S)-cytosin-lyl-1,3-oxothiolane salicylic acid salt (Lamivudine Salicylate) 2R-(HYDROXYMETHYL)-5(S)-CYTOSIN-1-YL-[1,3]-OXATHIOLANE SALICYLIC ACID SALT (2R-Cis)-4-Amino-1[2-(Hydroxymethyl)-1,3-Oxathiolan-5-Yl]-2(1H)-PyrimidinoneSalicylateMonohydrate Lamivudine Salicylate (CTS) (2R, 5S) -2-(Hydroxymethyl)-5-(4-amino-2-oxo-1(2H)-pyrimidinyl)-1,3-oxathiolane salicylate

Description	Lamivudine (BCH-189) salicylate is an orally active nucleoside reverse transcriptase inhibitor (NRTI). Lamivudine salicylate can inhibit HIV reverse transcriptase 1/2 and also the reverse transcriptase of hepatitis B virus. Lamivudine salicylate can penetrate the CNS[1][2].
Related Catalog	Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection Signaling Pathways >> Anti-infection >> HBV Signaling Pathways >> Anti-infection >> Reverse Transcriptase
References	[1]. Li, Y.C., [A clinical study on lamivudine treatment for advanced schistosomisis with chronic B hepatits]. Zhongguo Xue Xi Chong Bing Fang Zhi Za Zhi, 2013. 25(5): p. 548-9, 551. [2]. Zhang, C.E., et al., [Effects of lamivudine on growth of intestinal characteristic bacteria by microcalorimetry in vitro]. Yao Xue Xue Bao, 2013. 48(10): p. 1590-4.

147027-10-9

69-72-7

173522-96-8

Literature: WO2009/69012 A1, ; Page/Page column 22-23 ;

134678-17-4

69-72-7

173522-96-8

Literature: WO2009/69011 A1, ; Page/Page column 17-18 ;