Name | 3-(azepan-1-yl)-9-(dimethylamino)pyrido[1,2]thieno[3,4-d]pyrimidin-4-one |
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Synonyms | BU 224 hydrochloride |
Description | A-841720 is a potent, non-competitive and selective mGlu1 receptor antagonist with an IC50 of 10 nM for human mGlu1 receptor. A-841720 displays 34-fold selectivity over mGlu5 (IC50 of 342 nM), and no significant activity at a range of other neurotransmitter receptors, ion channels, and transporters. A-841720 has the potential for chronic pain research[1][2]. |
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Related Catalog | |
Target |
Human mGluR1:10 nM (IC50) human mGluR5:342 nM (IC50) |
References |
Molecular Formula | C17H21N5OS |
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Molecular Weight | 343.44700 |
Exact Mass | 343.14700 |
PSA | 82.50000 |
LogP | 2.64920 |
RIDADR | NONH for all modes of transport |
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Precursor 4 | |
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DownStream 0 |