A 841720
Modify Date: 2024-01-14 18:47:00
A 841720 structure
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Common Name | A 841720 | ||
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| CAS Number | 869802-58-4 | Molecular Weight | 343.44700 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C17H21N5OS | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of A 841720A-841720 is a potent, non-competitive and selective mGlu1 receptor antagonist with an IC50 of 10 nM for human mGlu1 receptor. A-841720 displays 34-fold selectivity over mGlu5 (IC50 of 342 nM), and no significant activity at a range of other neurotransmitter receptors, ion channels, and transporters. A-841720 has the potential for chronic pain research[1][2]. |
| Name | 3-(azepan-1-yl)-9-(dimethylamino)pyrido[1,2]thieno[3,4-d]pyrimidin-4-one |
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| Synonym | More Synonyms |
| Description | A-841720 is a potent, non-competitive and selective mGlu1 receptor antagonist with an IC50 of 10 nM for human mGlu1 receptor. A-841720 displays 34-fold selectivity over mGlu5 (IC50 of 342 nM), and no significant activity at a range of other neurotransmitter receptors, ion channels, and transporters. A-841720 has the potential for chronic pain research[1][2]. |
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| Related Catalog | |
| Target |
Human mGluR1:10 nM (IC50) human mGluR5:342 nM (IC50) |
| References |
| Molecular Formula | C17H21N5OS |
|---|---|
| Molecular Weight | 343.44700 |
| Exact Mass | 343.14700 |
| PSA | 82.50000 |
| LogP | 2.64920 |
| RIDADR | NONH for all modes of transport |
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![3-AMINO-4-DIMETHYLAMINO-THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID METHYL ESTER structure](https://www.chemsrc.com/caspic/239/331857-03-5.png)
| BU 224 hydrochloride |