Name | 4-amino-1-[(2S,4S,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]pyrimidin-2-one,hydrochloride |
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Synonyms |
4-Amino-1-(2-deoxy-2,2-difluoro-|A-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone Hydrochloride
2'-deoxy-2',2'-difluorocytidine hydrochloride 1'-Epi Gemcitabine Hydrochloride |
Description | 1'-epi Gemcitabine hydrochloride is the inactive isomer of Gemcitabine hydrochloride (HY-B0003), and can be used as an experimental control. Gemcitabine Hydrochloride (LY 188011 Hydrochloride) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine Hydrochloride inhibits DNA synthesis and repair, resulting in autophagyand apoptosis[1][2]. |
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Related Catalog | |
References |
Molecular Formula | C9H12ClF2N3O4 |
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Molecular Weight | 299.66 |
Exact Mass | 299.04800 |
PSA | 110.60000 |
LogP | 0.09460 |
~% 122111-05-1 |
Literature: DR. REDDY'S LABORATORIES LTD.; DR. REDDY'S LABORATORIES, INC. Patent: WO2007/117760 A2, 2007 ; Location in patent: Page/Page column 21 ; |
~% 122111-05-1 |
Literature: POLTURI, Ramesh, Babu; VENKATA, Subramanian, Hariharakrishnan; BETINI, Ramesh Patent: WO2005/95430 A1, 2005 ; Location in patent: Page/Page column 18-20 ; |
Precursor 3 | |
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DownStream 0 |