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138831-86-4

138831-86-4 structure
138831-86-4 structure
  • Name: OVA Peptide 257-264
  • Chemical Name: h-ser-ile-ile-asn-phe-glu-lys-leu-oh
  • CAS Number: 138831-86-4
  • Molecular Formula: C45H74N10O13
  • Molecular Weight: 963.12800
  • Catalog: Peptides
  • Create Date: 2018-10-21 17:55:04
  • Modify Date: 2024-01-02 12:21:30
  • OVA Peptide (257-264) is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide from ovalbumin presented by the class I MHC molecule, H-2Kb.
Name h-ser-ile-ile-asn-phe-glu-lys-leu-oh
Synonyms Ovalbumin (257-264) chicken
OVALBUMIN(257-264) ANTIGEN PEPTIDE
OVA PEPTIDE (257-264)
SIINFEKL
CHICKEN OVALBUMIN FRAGMENT (257-264)
SER-ILE-ILE-ASN-PHE-GLU-LYS-LEU
OVA (257-264) (CHICKEN)
H2N-SIINFEKL-OH
OVA (257-264)
OVALBUMIN (257-264) (CHICKEN)
Description OVA Peptide (257-264) is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide from ovalbumin presented by the class I MHC molecule, H-2Kb.
Related Catalog
In Vitro TAP1-I- and C57BL/6 macrophages may process Crl-OVA and full-length OVA in different cellular compartments and that the protein context of the OVA Peptide (257-264) epitope influences the extent of TAP-independent processing for MHC class I presentation. OVA Peptide (257-264) epitope is presented with a differential dependence on the TAP transporter depending on the protein context of the OVA epitope: OVA Peptide (257-264) contained within the MBPCrl-OVA or Crl-OVA bacterial fusion proteins is presented with little dependence on the TAP transporter, while OVA Peptide (257-264) contained within full-length ovalbumin is largely dependent on the TAP transporter, regardless of whether recombinant OVA is expressed in bacteria or the native protein is coupled to polystyrene beads[1].
Cell Assay TAPl-/- or C57BL/6 macrophages are co-incubated with either bacteria or polystyrene beads containing the 257-264 epitope from ovalbumin [OVA Peptide (257-264)], which binds the mouse class I molecule Kb. The source of the OVA(257-264) epitope is either the Crl-OVA(257-264) (Crl-OVA) fusion protein, the maltose binding protein (MBP)-Crl-OVA fusion protein, native OVA or bacterial recombinant OVA (rOVA); Crl-OVA, MBP-Crl-OVA and rOVA are each expressed in bacteria, and Crl-OVA and MBP-Crl-OVA purified from bacterial lysates and native egg OVA are coated onto polystyrene beads[1].
References

[1]. Wick MJ, et al. Major histocompatibility complex class I presentation of ovalbumin peptide 257-264 from exogenous sources: protein context influences the degree of TAP-independent presentation. Eur J Immunol. 1996 Nov;26(11):2790-9.
Molecular Formula C45H74N10O13
Molecular Weight 963.12800
Exact Mass 962.54400
PSA 393.66000
LogP 2.87160
Storage condition 2-8℃

Chemsrc provides CAS#:138831-86-4 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 138831-86-4 | Chemsrc address: https://m.chemsrc.com/en/baike/835561.html

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