OVA Peptide 257-264 structure
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Common Name | OVA Peptide 257-264 | ||
|---|---|---|---|---|
| CAS Number | 138831-86-4 | Molecular Weight | 963.12800 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C45H74N10O13 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of OVA Peptide 257-264OVA Peptide (257-264) is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide from ovalbumin presented by the class I MHC molecule, H-2Kb. |
| Name | h-ser-ile-ile-asn-phe-glu-lys-leu-oh |
|---|---|
| Synonym | More Synonyms |
| Description | OVA Peptide (257-264) is a class I (Kb)-restricted peptide epitope of OVA, an octameric peptide from ovalbumin presented by the class I MHC molecule, H-2Kb. |
|---|---|
| Related Catalog | |
| In Vitro | TAP1-I- and C57BL/6 macrophages may process Crl-OVA and full-length OVA in different cellular compartments and that the protein context of the OVA Peptide (257-264) epitope influences the extent of TAP-independent processing for MHC class I presentation. OVA Peptide (257-264) epitope is presented with a differential dependence on the TAP transporter depending on the protein context of the OVA epitope: OVA Peptide (257-264) contained within the MBPCrl-OVA or Crl-OVA bacterial fusion proteins is presented with little dependence on the TAP transporter, while OVA Peptide (257-264) contained within full-length ovalbumin is largely dependent on the TAP transporter, regardless of whether recombinant OVA is expressed in bacteria or the native protein is coupled to polystyrene beads[1]. |
| Cell Assay | TAPl-/- or C57BL/6 macrophages are co-incubated with either bacteria or polystyrene beads containing the 257-264 epitope from ovalbumin [OVA Peptide (257-264)], which binds the mouse class I molecule Kb. The source of the OVA(257-264) epitope is either the Crl-OVA(257-264) (Crl-OVA) fusion protein, the maltose binding protein (MBP)-Crl-OVA fusion protein, native OVA or bacterial recombinant OVA (rOVA); Crl-OVA, MBP-Crl-OVA and rOVA are each expressed in bacteria, and Crl-OVA and MBP-Crl-OVA purified from bacterial lysates and native egg OVA are coated onto polystyrene beads[1]. |
| References |
| Molecular Formula | C45H74N10O13 |
|---|---|
| Molecular Weight | 963.12800 |
| Exact Mass | 962.54400 |
| PSA | 393.66000 |
| LogP | 2.87160 |
| Storage condition | 2-8℃ |
| Ovalbumin (257-264) chicken |
| OVALBUMIN(257-264) ANTIGEN PEPTIDE |
| OVA PEPTIDE (257-264) |
| SIINFEKL |
| CHICKEN OVALBUMIN FRAGMENT (257-264) |
| SER-ILE-ILE-ASN-PHE-GLU-LYS-LEU |
| OVA (257-264) (CHICKEN) |
| H2N-SIINFEKL-OH |
| OVA (257-264) |
| OVALBUMIN (257-264) (CHICKEN) |