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349-49-5

349-49-5 structure
349-49-5 structure
  • Name: 4-(Trifluoromethyl)thiazol-2-amine
  • Chemical Name: 4-(trifluoromethyl)-1,3-thiazol-2-amine
  • CAS Number: 349-49-5
  • Molecular Formula: C4H3F3N2S
  • Molecular Weight: 168.140
  • Create Date: 2018-09-12 15:03:36
  • Modify Date: 2024-01-03 09:34:31

Name 4-(trifluoromethyl)-1,3-thiazol-2-amine
Synonyms 4-(trifluoromethyl)-1,3-thiazole-2-amine
2-Amino-4-trifluoromethyl-1,3-thiazole
4-(Trifluoromethyl)thiazol-2-amine
2-Amino-4-(trifluoromethyl)-1,3-thiazole
2-Amino-4-trifluoromethylthiazole
2-Amino-4-trifluoromethylthiazole hydrobromide
MFCD00832759
2-amino-4-(trifluoromethyl)thiazole
4-Trifluormethyl-thiazol-2-ylamin
4-(Trifluoromethyl)-1,3-thiazol-2-amine
4-(Trifluoromethyl)-2-thiazolamine
4-trifluoromethyl-thiazol-2-ylamine
4-Trifluoromethyl-thiazole-2ylamine
2-Thiazolamine, 4-(trifluoromethyl)-
Density 1.6±0.1 g/cm3
Boiling Point 214.0±35.0 °C at 760 mmHg
Melting Point 60-62°C
Molecular Formula C4H3F3N2S
Molecular Weight 168.140
Flash Point 83.2±25.9 °C
Exact Mass 167.996902
PSA 67.15000
LogP 0.95
Vapour Pressure 0.2±0.4 mmHg at 25°C
Index of Refraction 1.504
Hazard Codes Xi: Irritant;
Risk Phrases R20/21/22
Safety Phrases S26-S36/37/39
WGK Germany 3.0
HS Code 2934100090

~79%

349-49-5 structure

349-49-5

Literature: ELI LILLY AND COMPANY Patent: WO2008/36579 A1, 2008 ; Location in patent: Page/Page column 43 ; WO 2008/036579 A1

~30%

349-49-5 structure

349-49-5

Literature: ACHAOGEN, INC.; WAGMAN, Allan, Scott; MOSER, Heinz, Ernst Patent: WO2010/30811 A2, 2010 ; Location in patent: Page/Page column 92 ; WO 2010/030811 A2

~29%

349-49-5 structure

349-49-5

Literature: ACHAOGEN, INC.; MOSER, Heinz, E.; WAGMAN, Allan, S. Patent: WO2010/123997 A1, 2010 ; Location in patent: Page/Page column 65; 88 ; WO 2010/123997 A1

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349-49-5 structure

349-49-5

Literature: Journal of Organic Chemistry, , vol. 20, p. 499,505

~91%

349-49-5 structure

349-49-5

Literature: Laduron, Frederic; Janousek, Zdenek; Viehe, Heinz, G. Journal of Fluorine Chemistry, 1995 , vol. 73, # 1 p. 83 - 86

~90%

349-49-5 structure

349-49-5

Literature: Stachulski, Andrew V.; Pidathala, Chandrakala; Row, Eleanor C.; Sharma, Raman; Berry, Neil G.; Lawrenson, Alexandre S.; Moores, Shelley L.; Iqbal, Mazhar; Bentley, Joanne; Allman, Sarah A.; Edwards, Geoffrey; Helm, Alison; Hellier, Jennifer; Korba, Brent E.; Semple, J. Edward; Rossignol, Jean-Francois Journal of Medicinal Chemistry, 2011 , vol. 54, # 24 p. 8670 - 8680
HS Code 2934100090
Summary 2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%