2627-62-5
2627-62-5 structure
- Name: Adenosine,2'-chloro-2'-deoxy-
- Chemical Name: (2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-chloro-2-(hydroxymethyl)oxolan-3-ol
- CAS Number: 2627-62-5
- Molecular Formula: C10H12ClN5O3
- Molecular Weight: 285.69
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
- Create Date: 2017-07-07 23:12:23
- Modify Date: 2024-01-10 17:55:02
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2’-Chloro-2’-deoxyadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
| Name | (2R,3R,4R,5R)-5-(6-aminopurin-9-yl)-4-chloro-2-(hydroxymethyl)oxolan-3-ol |
|---|---|
| Synonyms |
2'-deoxy-2'-chloroadenosine
2'-Chlor-2'-deoxy-adenosin Adenosine,2'-chloro-2'-deoxy 2'-chloro-2'-deoxy-adenosine |
| Description | 2’-Chloro-2’-deoxyadenosine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1]. |
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| Related Catalog | |
| References |
| Density | 2.03g/cm3 |
|---|---|
| Boiling Point | 678.2ºC at 760mmHg |
| Molecular Formula | C10H12ClN5O3 |
| Molecular Weight | 285.69 |
| Flash Point | 364ºC |
| Exact Mass | 285.06300 |
| PSA | 119.31000 |
| Vapour Pressure | 2.54E-19mmHg at 25°C |
| Index of Refraction | 1.87 |
|
~82%
2627-62-5 |
| Literature: Fukukawa; Uedao; Hirano Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 5 p. 1582 - 1592 |
|
~%
2627-62-5 |
| Literature: Fukukawa; Uedao; Hirano Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 5 p. 1582 - 1592 |
|
~%
2627-62-5 |
| Literature: Fukukawa; Uedao; Hirano Chemical and Pharmaceutical Bulletin, 1983 , vol. 31, # 5 p. 1582 - 1592 |
| Precursor 3 | |
|---|---|
| DownStream 0 | |