4300-43-0
4300-43-0 structure
- Name: MMV665852
- Chemical Name: 1,3-bis(3,4-dichlorophenyl)urea
- CAS Number: 4300-43-0
- Molecular Formula: C13H8Cl4N2O
- Molecular Weight: 350.02700
- Create Date: 2018-12-21 11:00:02
- Modify Date: 2025-08-25 16:49:13
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MMV665852 is an antischistosomal agent. It has been shown to inhibit worm viability in vitro and reduce worm burden in S. mansoni-infected mice.
| Name | 1,3-bis(3,4-dichlorophenyl)urea |
|---|---|
| Synonyms |
GNF-PF-2903
1,3-BIS-(3,4-DICHLORO-PHENYL)-UREA Urea-based compound,10 |
| Density | 1.608g/cm3 |
|---|---|
| Boiling Point | 369.2ºC at 760 mmHg |
| Molecular Formula | C13H8Cl4N2O |
| Molecular Weight | 350.02700 |
| Flash Point | 177.1ºC |
| Exact Mass | 347.93900 |
| PSA | 41.13000 |
| LogP | 6.09020 |
| Index of Refraction | 1.705 |
| Storage condition | 2-8°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H319-H413 |
| Precautionary Statements | P305 + P351 + P338 |
| RIDADR | UN 3077 9 / PGIII |
| HS Code | 2924299090 |
|
~88%
4300-43-0 |
| Literature: McElroy, Nathan R.; Jurs, Peter C.; Morisseau, Christophe; Hammock, Bruce D. Journal of Medicinal Chemistry, 2003 , vol. 46, # 6 p. 1066 - 1080 |
|
~40%
4300-43-0 |
| Literature: Supuran, Claudiu T.; Scozzafava, Andrea; Jurca, Bogdan C.; Ilies, Marc A. European Journal of Medicinal Chemistry, 1998 , vol. 33, # 2 p. 83 - 93 |
|
~%
4300-43-0 |
| Literature: Perret Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1932 , vol. 194, p. 975 |
|
~%
4300-43-0 |
| Literature: Cegan, Alexandr; Vecera, Miroslav Collection of Czechoslovak Chemical Communications, 1984 , vol. 49, # 6 p. 1521 - 1528 |
|
~%
4300-43-0 |
| Literature: Cegan, Alexandr; Vecera, Miroslav Collection of Czechoslovak Chemical Communications, 1984 , vol. 49, # 6 p. 1521 - 1528 |
|
~%
4300-43-0 |
| Literature: Chimishkyan, A. L.; Svetlova, L. P.; Leonova, T. V.; Gluyaev, N. D. J. Gen. Chem. USSR (Engl. Transl.), 1984 , vol. 54, # 7 p. 1477 - 1481,1317 - 1320 |
| HS Code | 2924299090 |
|---|---|
| Summary | 2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0% |