203661-69-2
203661-69-2 structure
- Name: tert-butyl 2-oxo-7-azaspiro[3.5]nonane-7-carboxylate
- Chemical Name: 2-Oxo-7-azaspiro[3.5]nonane-7-carboxylate tert-butyl ester
- CAS Number: 203661-69-2
- Molecular Formula: C10H12F3NO3
- Molecular Weight: 251.202
- Create Date: 2018-12-16 16:26:30
- Modify Date: 2024-01-05 19:30:36
| Name | 2-Oxo-7-azaspiro[3.5]nonane-7-carboxylate tert-butyl ester |
|---|---|
| Synonyms |
7-Azaspiro[3.5]nonane-7-carboxylic acid, 2-oxo-, trifluoromethyl ester
tert-butyl 2-oxo-7-azaspiro[3.5]nonane-7-carboxylate Trifluoromethyl 2-oxo-7-azaspiro[3.5]nonane-7-carboxylate |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 274.2±40.0 °C at 760 mmHg |
| Melting Point | 55-56°C |
| Molecular Formula | C10H12F3NO3 |
| Molecular Weight | 251.202 |
| Flash Point | 119.7±27.3 °C |
| Exact Mass | 251.076935 |
| PSA | 46.61000 |
| LogP | 1.36 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.474 |
| Storage condition | 2-8°C |
| Hazard Codes | Xi |
|---|---|
| RIDADR | NONH for all modes of transport |
| HS Code | 2933990090 |
|
~98%
203661-69-2 |
| Literature: Brown, Dean G.; Bernstein, Peter R.; Griffin, Andrew; Wesolowski, Steve; Labrecque, Denis; Tremblay, Maxime C.; Sylvester, Mark; Mauger, Russell; Edwards, Phillip D.; Throner, Scott R.; Folmer, James J.; Cacciola, Joseph; Scott, Clay; Lazor, Lois A.; Pourashraf, Mehrnaz; Santhakumar, Vijayaratnam; Potts, William M.; Sydserff, Simon; Giguere, Pascall; Levesque, Carine; Dasser, Mohammed; Groblewski, Thierry Journal of Medicinal Chemistry, 2014 , vol. 57, # 3 p. 733 - 758 |
|
~14%
203661-69-2 |
| Literature: BETA PHARMA CANADA INC.; WANG, Zhaoyin; LI, Lianhai; WANG, Zhigang Patent: WO2013/13308 A1, 2013 ; Location in patent: Paragraph 00199-00201 ; WO 2013/013308 A1 |
|
~%
203661-69-2 |
| Literature: Chemical and Pharmaceutical Bulletin, , vol. 52, # 6 p. 675 - 687 |
| Precursor 2 | |
|---|---|
| DownStream 3 | |
![tert-butyl 2-cyano-7-azaspiro[3.5]nonane-7-carboxylate structure](https://www.chemsrc.com/caspic/365/203662-66-2.png)
![tert-butyl 2-hydroxy-7-azaspiro[3.5]nonane-7-carboxylate structure](https://www.chemsrc.com/caspic/388/240401-28-9.png)
![TERT-BUTYL 2-AMINO-7-AZASPIRO[3.5]NONANE-7-CARBOXYLATE structure](https://www.chemsrc.com/caspic/374/1239319-82-4.png)
| HS Code | 2933990090 |
|---|---|
| Summary | 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |