1260635-77-5

1260635-77-5 structure

Name: coumarin-SAHA
Chemical Name: N'-hydroxy-N-(4-methyl-2-oxochromen-7-yl)octanediamide
CAS Number: 1260635-77-5
Molecular Formula: C₁₈H₂₂N₂O₅
Molecular Weight: 346.378
Catalog: Signaling Pathways Epigenetics Histone Acetyltransferase
Create Date: 2017-02-19 01:42:23
Modify Date: 2024-01-02 05:46:03
Coumarin-SAHA is a fluorescent probe for determining the binding affinities (kd) and the dissociation off-rates (koff) of the HDAC8-inhibitor complexes[1].

Name	N'-hydroxy-N-(4-methyl-2-oxochromen-7-yl)octanediamide
Synonyms	N-Hydroxy-N'-(4-methyl-2-oxo-2H-chromen-7-yl)octanediamide Octanediamide, N-hydroxy-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)- Coumarin Suberoylanilide Hydroxamic Acid Coumarin-SAHA

Description	Coumarin-SAHA is a fluorescent probe for determining the binding affinities (kd) and the dissociation off-rates (koff) of the HDAC8-inhibitor complexes[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Epigenetics >> Histone Acetyltransferase
References	[1]. Raushan K Singh, et al. Coumarin-suberoylanilide hydroxamic acid as a fluorescent probe for determining binding affinities and off-rates of histone deacetylase inhibitors. Anal Biochem