701947-53-7
701947-53-7 structure
- Name: DM-PIT-1
- Chemical Name: 3,5-dimethyl PIT-1
- CAS Number: 701947-53-7
- Molecular Formula: C16H15N3O4S
- Molecular Weight: 345.373
- Create Date: 2017-01-05 10:39:23
- Modify Date: 2025-09-25 17:48:07
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DM-PIT-1 is a specific PIP3 antagonist that disrupts PIP3/Akt PH domain, PIP3/PDK1 PH domain, and PIP3/GRP1 PH domain with IC50 of 27.1 uM, 80.5 uM, and 35.5 uM, respectively.
| Name | 3,5-dimethyl PIT-1 |
|---|---|
| Synonyms |
N-{[(2-hydroxy-5-nitrophenyl)amino]carbonothioyl}-3,5-dimethylbenzamide
DM-PIT-1 N-(2-hydroxy-5-nitrophenylcarbamothioyl)-3,5-dimethylbenzamide Benzamide, N-[[(2-hydroxy-5-nitrophenyl)amino]thioxomethyl]-3,5-dimethyl- |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Molecular Formula | C16H15N3O4S |
| Molecular Weight | 345.373 |
| Exact Mass | 345.078339 |
| PSA | 139.27000 |
| LogP | 4.12 |
| Index of Refraction | 1.711 |