161923-50-8

161923-50-8 structure

Name: 6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine
Chemical Name: 6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine
CAS Number: 161923-50-8
Molecular Formula: C₁₆H₁₇ClN₄O₈
Molecular Weight: 428.78
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2017-11-15 19:39:41
Modify Date: 2024-04-03 21:19:08
6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine
Synonyms	6-chloropyrazine-2-ylhydrazine 2-chloro-6-hydrazinopyridazine 2-Hydrazino-6-chlorpyrazin 2-Chloro-6-hydrazinylpyrazine 2',3',5'-triacetyl-6-chloroguanosine 6-chloro-2-hydrazinopyrazine 2-chloro-6-hydrazino-pyrazine

Description	6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

16321-99-6

~97%

161923-50-8

Literature: Moorman, Allan R. Patent: US2003/199686 A1, 2003 ; Location in patent: Page/Page column 6 ;