6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine

Modify Date: 2024-04-03 21:19:08

6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine structure	Common Name	6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine
	CAS Number	161923-50-8	Molecular Weight	428.78
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₆H₁₇ClN₄O₈	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine

6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine
Synonym	More Synonyms

Description	6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-β-D-ribofuranosyl)purine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Molecular Formula	C₁₆H₁₇ClN₄O₈
Molecular Weight	428.78
Exact Mass	428.07300
PSA	151.96000
LogP	0.50920
Index of Refraction	1.678

2',3',5'-Tri-O-...

CAS#:16321-99-6

~97%

6-Chloro-2-hydr...

CAS#:161923-50-8

Literature: Moorman, Allan R. Patent: US2003/199686 A1, 2003 ; Location in patent: Page/Page column 6 ;

Precursor 1
CAS#:16321-99-6 2',3',5'-Tri-O-...
DownStream 1
CAS#:1818-71-9 Crotonoside

6-chloropyrazine-2-ylhydrazine

2-chloro-6-hydrazinopyridazine

2-Hydrazino-6-chlorpyrazin

2-Chloro-6-hydrazinylpyrazine

2',3',5'-triacetyl-6-chloroguanosine

6-chloro-2-hydrazinopyrazine

2-chloro-6-hydrazino-pyrazine

6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine

Use of 6-Chloro-2-hydroxy-9-(2',3',5'-tri-O-acetyl-b-D-ribofuranosyl)purine

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