16514-83-3

16514-83-3 structure

Name: Squalane-d62
Chemical Name: 2,6,10,15,19,23-hexamethyltetracosane-d62
CAS Number: 16514-83-3
Molecular Formula: C₃₀D₆₂
Molecular Weight: 485.195
Catalog: Research Areas Cancer
Create Date: 2018-08-14 18:21:19
Modify Date: 2024-01-06 13:08:01
Squalane-d62 is the deuterium labeled Squalane[1]. Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities[2].

Name	2,6,10,15,19,23-hexamethyltetracosane-d62
Synonyms	Tetracosane-1,1,1,2,3,3,4,4,5,5,6,7,7,8,8,9,9,10,11,11,12,12,13,13,14,14,15,16,16,17,17,18,18,19,20,20,21,21,22,22,23,24,24,24-d, 2,6,10,15,19,23-hexa(methyl-d)- dohexacontadeuterio-squalane SQAFLFQPQRF-NH2 2,6,10,15,19,23-Hexakis[(H)methyl](H)tetracosane 2H,6H,10H,15H,19H,23H-dotriacontadeuterio-2,6,10,15,19,23-hexakis-trideuteriomethyl-tetracosane H-SER-GLN-ALA-PHE-LEU-PHE-GLN-PRO-GLN-ARG-PHE-NH2

Description	Squalane-d62 is the deuterium labeled Squalane[1]. Squalane, found in certain fish oils (especially shark liver oil), and some vegetable oils, is a saturated derivative of Squalene. Squalane shows anticancer, antioxidant, skin hydrating, and emollient activities[2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Kim SK, et al. Biological importance and applications of squalene and squalane. Adv Food Nutr Res. 2012;65:223-33.