1092484-69-9
1092484-69-9 structure
- Name: Fenofibric acid-d6
- Chemical Name: 2-[4-(4-chlorobenzoyl)phenoxy]-3,3,3-trideuterio-2-(trideuteriomethyl)propanoic acid
- CAS Number: 1092484-69-9
- Molecular Formula: C17H9ClD6O4
- Molecular Weight: 324.78900
- Catalog: Signaling Pathways Cell Cycle/DNA Damage PPAR
- Create Date: 2018-03-02 08:00:00
- Modify Date: 2024-01-09 03:29:02
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Fenofibric acid-d6 (FNF acid-d6) is the deuterium labeled Fenofibric acid. Fenofibric acid, an active metabolite of fenofibrate, is a PPAR activitor, with EC50s of 22.4 µM, 1.47 µM, and 1.06 µM for PPARα, PPARγ and PPARδ, respectively; Fenofibric acid also inhibits COX-2 enzyme activity, with an IC50 of 48 nM.
| Name | 2-[4-(4-chlorobenzoyl)phenoxy]-3,3,3-trideuterio-2-(trideuteriomethyl)propanoic acid |
|---|---|
| Synonyms |
Procetofenic Acid-d6
Fenofibric-d6 Acid FNF Acid-d6 |
| Description | Fenofibric acid-d6 (FNF acid-d6) is the deuterium labeled Fenofibric acid. Fenofibric acid, an active metabolite of fenofibrate, is a PPAR activitor, with EC50s of 22.4 µM, 1.47 µM, and 1.06 µM for PPARα, PPARγ and PPARδ, respectively; Fenofibric acid also inhibits COX-2 enzyme activity, with an IC50 of 48 nM. |
|---|---|
| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
| Molecular Formula | C17H9ClD6O4 |
|---|---|
| Molecular Weight | 324.78900 |
| Exact Mass | 324.10400 |
| PSA | 63.60000 |
| LogP | 3.81300 |