35144-64-0

35144-64-0 structure

Name: aldophosphamide
Chemical Name: 3-[amino-[bis(2-chloroethyl)amino]phosphoryl]oxypropanal
CAS Number: 35144-64-0
Molecular Formula: C₇H₁₅Cl₂N₂O₃P
Molecular Weight: 277.09
Catalog: Research Areas Cancer
Create Date: 2017-03-06 04:41:01
Modify Date: 2024-01-06 11:19:27
Aldophosphamide (NSC 254) is a cyclophosphamide metabolite. Aldophosphamide is cleaved intracellularly to phosphoramide mustard, an active metabolite with direct cytotoxicity, and acrolein. Aldophosphamide has potential for cancer research[1].

Name	3-[amino-[bis(2-chloroethyl)amino]phosphoryl]oxypropanal
Synonyms	Aldophosphamide

Description	Aldophosphamide (NSC 254) is a cyclophosphamide metabolite. Aldophosphamide is cleaved intracellularly to phosphoramide mustard, an active metabolite with direct cytotoxicity, and acrolein. Aldophosphamide has potential for cancer research[1].
Related Catalog	Research Areas >> Cancer
References	[1]. Fenselau C, et al. Identification of aldophosphamide as a metabolite of cyclophosphamide in vitro and in vivo in humans. Cancer Res. 1977 Aug;37(8 Pt 1):2538-43.