39959-66-5

39959-66-5 structure

Name: LY 78335
Chemical Name: 1-(2,3-dichlorophenyl)ethanamine,hydrochloride
CAS Number: 39959-66-5
Molecular Formula: C₈H₁₀Cl₃N
Molecular Weight: 226.53100
Catalog: Research Areas Cardiovascular Disease
Create Date: 2017-04-24 10:01:41
Modify Date: 2024-04-05 11:14:39
1-(2,3-Dichlorophenyl)ethanamine hydrochloride is a phenylethanolamine N-methyltransferase (PNMT) inhibitor. 1-(2,3-Dichlorophenyl)ethanamine hydrochloride effectively reduces blood pressure of spontaneously hypertensive. 1-(2,3-Dichlorophenyl)ethanamine hydrochloride can be used for the research of blood pressure[1].

Name	1-(2,3-dichlorophenyl)ethanamine,hydrochloride
Synonyms	DCMB hydrochloride

Description	1-(2,3-Dichlorophenyl)ethanamine hydrochloride is a phenylethanolamine N-methyltransferase (PNMT) inhibitor. 1-(2,3-Dichlorophenyl)ethanamine hydrochloride effectively reduces blood pressure of spontaneously hypertensive. 1-(2,3-Dichlorophenyl)ethanamine hydrochloride can be used for the research of blood pressure[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Others >> Others
In Vivo	1-(2,3-Dichlorophenyl)ethanamine hydrochloride (50 mg/kg; i.p. once daily for three days) effects blood pressure of spontaneously hypertensive rats [1]. Animal Model: Adult spontaneously hypertensive rats (SHR) and Wistar Kyoto rats[1] Dosage: 50 mg/kg Administration: Intraperitoneal injection; 50 mg/kg; once daily, for 3 consecutive days Result: Significantly reduced of the blood pressure in spontaneously hypertensive rats, but showed no significant changes in Wistar-Kyoto rats.