LY 78335

Modify Date: 2024-04-05 11:14:39

LY 78335 Structure
LY 78335 structure
Common Name LY 78335
CAS Number 39959-66-5 Molecular Weight 226.53100
Density N/A Boiling Point N/A
Molecular Formula C8H10Cl3N Melting Point N/A
MSDS N/A Flash Point N/A

 Use of LY 78335


1-(2,3-Dichlorophenyl)ethanamine hydrochloride is a phenylethanolamine N-methyltransferase (PNMT) inhibitor. 1-(2,3-Dichlorophenyl)ethanamine hydrochloride effectively reduces blood pressure of spontaneously hypertensive. 1-(2,3-Dichlorophenyl)ethanamine hydrochloride can be used for the research of blood pressure[1].

 Names

Name 1-(2,3-dichlorophenyl)ethanamine,hydrochloride
Synonym More Synonyms

 LY 78335 Biological Activity

Description 1-(2,3-Dichlorophenyl)ethanamine hydrochloride is a phenylethanolamine N-methyltransferase (PNMT) inhibitor. 1-(2,3-Dichlorophenyl)ethanamine hydrochloride effectively reduces blood pressure of spontaneously hypertensive. 1-(2,3-Dichlorophenyl)ethanamine hydrochloride can be used for the research of blood pressure[1].
Related Catalog
In Vivo 1-(2,3-Dichlorophenyl)ethanamine hydrochloride (50 mg/kg; i.p. once daily for three days) effects blood pressure of spontaneously hypertensive rats [1]. Animal Model: Adult spontaneously hypertensive rats (SHR) and Wistar Kyoto rats[1] Dosage: 50 mg/kg Administration: Intraperitoneal injection; 50 mg/kg; once daily, for 3 consecutive days Result: Significantly reduced of the blood pressure in spontaneously hypertensive rats, but showed no significant changes in Wistar-Kyoto rats.

 Chemical & Physical Properties

Molecular Formula C8H10Cl3N
Molecular Weight 226.53100
Exact Mass 224.98800
PSA 26.02000
LogP 4.51540

 Synonyms

DCMB hydrochloride
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