220001-53-6

220001-53-6 structure

Name: 7-Benzyloxy-4-(trifluoromethyl)coumarin
Chemical Name: 7-phenylmethoxy-4-(trifluoromethyl)chromen-2-one
CAS Number: 220001-53-6
Molecular Formula: C₁₇H₁₁F₃O₃
Molecular Weight: 320.26300
Catalog: Signaling Pathways Metabolic Enzyme/Protease Cytochrome P450
Create Date: 2017-01-29 06:15:26
Modify Date: 2024-01-21 10:49:09
7-Benzyloxy-4-(trifluoromethyl)coumarin (7-BFC) is a coumarin fluorescent substrate. 7-Benzyloxy-4-(trifluoromethyl)coumarin is a substrate for cDNA-expressed CYP1A2 and CYP3A4 and is metabolized to 7-hydroxy-4-trifluoromethylcoumarin (HFC). 7-Benzyloxy-4-(trifluoromethyl)coumarin is used for rapid CYP isoform metabolism and inhibition screening studies[1].

Name	7-phenylmethoxy-4-(trifluoromethyl)chromen-2-one
Synonyms	7-benzyloxy-trifluoromethyl coumarin 7-Benzyloxy-4-trifluoromethylcoumarin

Description	7-Benzyloxy-4-(trifluoromethyl)coumarin (7-BFC) is a coumarin fluorescent substrate. 7-Benzyloxy-4-(trifluoromethyl)coumarin is a substrate for cDNA-expressed CYP1A2 and CYP3A4 and is metabolized to 7-hydroxy-4-trifluoromethylcoumarin (HFC). 7-Benzyloxy-4-(trifluoromethyl)coumarin is used for rapid CYP isoform metabolism and inhibition screening studies[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Cytochrome P450 Research Areas >> Others
References	[1]. A B Renwick, et al. Metabolism of 7-benzyloxy-4-trifluoromethyl-coumarin by human hepatic cytochrome P450 isoforms. Xenobiotica. 2000 Oct;30(10):955-69.

575-03-1

100-39-0

~21%

220001-53-6