314245-65-3
314245-65-3 structure
- Name: migrastatin
- Chemical Name: migrastatin
- CAS Number: 314245-65-3
- Molecular Formula: C27H39NO7
- Molecular Weight: 489.60100
- Catalog: Research Areas Cancer
- Create Date: 2016-09-27 13:52:05
- Modify Date: 2024-01-09 10:17:19
-
Migrastatin is a typical Fascin1 inhibitor. Migrastatin is isolated from a cultured broth of Streptomyces sp. MK929-43F1. Migrastatin inhibits tumor cell migration[1][2].
| Name | migrastatin |
|---|---|
| Synonyms |
Migrastatin
4-[(5S)-5-[(2R,3Z,5R,6S,7S,8E,12E)-6-hydroxy-7-methoxy-3,5-dimethyl-14-oxo-1-oxacyclotetradeca-3,8,12-trien-2-yl]-4-oxohexyl]piperidine-2,6-dione 4-{(5S)-5-[(2R,3Z,5R,6S,7S,8E,12E)-6-hydroxy-7-methoxy-3,5-dimethyl-14-oxooxacyclotetradeca-3,8,12-trien-2-yl]-4-oxohexyl}piperidine-2,6-dione |
| Description | Migrastatin is a typical Fascin1 inhibitor. Migrastatin is isolated from a cultured broth of Streptomyces sp. MK929-43F1. Migrastatin inhibits tumor cell migration[1][2]. |
|---|---|
| Related Catalog | |
| Target |
Fascin1[1] |
| In Vitro | Migrastatin (100 μM) leads to the disorganization of the bundles. Migrastatin (100 μM; HCT-116 and DLD-1 cells) prevents cell migration[1]. |
| References |
| Molecular Formula | C27H39NO7 |
|---|---|
| Molecular Weight | 489.60100 |
| Exact Mass | 489.27300 |
| PSA | 122.49000 |
| LogP | 3.46690 |
| Hazard Codes | Xi |
|---|