5634-34-4

5634-34-4 structure
5634-34-4 structure
  • Name: Ambuphylline
  • Chemical Name: 2-amino-2-methylpropan-1-ol,1,3-dimethyl-7H-purine-2,6-dione
  • CAS Number: 5634-34-4
  • Molecular Formula: C11H19N5O3
  • Molecular Weight: 269.30000
  • Catalog: Signaling Pathways Metabolic Enzyme/Protease Phosphodiesterase (PDE)
  • Create Date: 2018-07-05 18:50:32
  • Modify Date: 2024-01-05 14:40:15
  • Ambuphylline (Bufylline) is a bronchodilator. Ambuphylline is a theophylline derivative possibly acting through phosphodiesterase inhibition. Ambuphylline can be used for the research of asthma and other lung diseases[1].

Name 2-amino-2-methylpropan-1-ol,1,3-dimethyl-7H-purine-2,6-dione
Synonyms Butaphyllamine
AMBUPHYLLINE
Bufylline
EINECS 227-077-5
Theophylline aminoisobutanol
Buthoid
Description Ambuphylline (Bufylline) is a bronchodilator. Ambuphylline is a theophylline derivative possibly acting through phosphodiesterase inhibition. Ambuphylline can be used for the research of asthma and other lung diseases[1].
Related Catalog
Boiling Point 454.1ºC at 760 mmHg
Molecular Formula C11H19N5O3
Molecular Weight 269.30000
Flash Point 228.4ºC
Exact Mass 269.14900
PSA 118.93000

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XH4375000
CAS REGISTRY NUMBER :
5634-34-4
LAST UPDATED :
199107
DATA ITEMS CITED :
2
MOLECULAR FORMULA :
C7-H8-N4-O2.C4-H11-N-O
MOLECULAR WEIGHT :
269.35
WISWESSER LINE NOTATION :
ZX1Q &622 &T56 BM DN FNVMVJ F H &621

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
600 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
JLCMAK Journal of Laboratory and Clinical Medicine. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1915- Volume(issue)/page/year: 31,1337,1946
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
163 mg/kg
TOXIC EFFECTS :
Behavioral - convulsions or effect on seizure threshold
REFERENCE :
JLCMAK Journal of Laboratory and Clinical Medicine. (C.V. Mosby Co., 11830 Westline Industrial Dr., St. Louis, MO 63141) V.1- 1915- Volume(issue)/page/year: 31,1337,1946