1216682-38-0

1216682-38-0 structure

Name: Lansoprazole Sulfide D4
Chemical Name: 4,5,6,7-tetradeuterio-2-[[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfanyl]-1H-benzimidazole
CAS Number: 1216682-38-0
Molecular Formula: C₁₆H₁₀D₄F₃N₃OS
Molecular Weight: 357.38700
Catalog: Signaling Pathways Anti-infection Bacterial
Create Date: 2016-12-28 21:36:23
Modify Date: 2024-01-22 19:10:30
Lansoprazole Sulfide D4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an active metabolite of the proton pump inhibitor Lansoprazole. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC50 values of 0.59 µM intracellularly and 0.46 µM in broth[1].

Name	4,5,6,7-tetradeuterio-2-[[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methylsulfanyl]-1H-benzimidazole
Synonyms	K 1252-d4 H 225/18-d4 2-[[[3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]thio]-1H-benzimidazole-d4 AG 1777-d4 Lansoprazole Sulfide-d4 [2H4]-Lansoprazole sulfide

Description	Lansoprazole Sulfide D4 is a deuterium labeled Lansoprazole Sulfide. Lansoprazole Sulfide is an active metabolite of the proton pump inhibitor Lansoprazole. Lansoprazole Sulfide is an orally active anti-TB (Mycobacterium tuberculosis) agent with IC50 values of 0.59 µM intracellularly and 0.46 µM in broth[1].
Related Catalog	Research Areas >> Inflammation/Immunology Signaling Pathways >> Membrane Transporter/Ion Channel >> Proton Pump Signaling Pathways >> Anti-infection >> Bacterial
Target	Proton pump[1] IC50: 0.59 µM (Mycobacterium tuberculosis intracellularly), 0.46 µM (Mycobacterium tuberculosis in broth)[1]
References	[1]. Mdanda S, et al. Lansoprazole-sulfide, pharmacokinetics of this promising anti-tuberculous agent. Biomed Chromatogr. 2017 Dec;31(12).