197513-96-5

197513-96-5 structure

Name: m-PEG4-aldehyde
Chemical Name: mPEG3-propionaldehyde
CAS Number: 197513-96-5
Molecular Formula: C₁₀H₂₀O₅
Molecular Weight: 220.26300
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2017-10-15 13:31:53
Modify Date: 2024-01-09 11:28:38
m-PEG4-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	mPEG3-propionaldehyde

Description	m-PEG4-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562