m-PEG4-aldehyde

Modify Date: 2024-01-09 11:28:38

m-PEG4-aldehyde Structure
m-PEG4-aldehyde structure
Common Name m-PEG4-aldehyde
CAS Number 197513-96-5 Molecular Weight 220.26300
Density N/A Boiling Point N/A
Molecular Formula C10H20O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG4-aldehyde


m-PEG4-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name mPEG3-propionaldehyde

 m-PEG4-aldehyde Biological Activity

Description m-PEG4-aldehyde is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C10H20O5
Molecular Weight 220.26300
Exact Mass 220.13100
PSA 53.99000
LogP 0.27160
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