61950-59-2

61950-59-2 structure

Name: (D-Trp8,D-Cys14)-Somatostatin-14
Chemical Name: (d-trp8,d-cys14)-somatostatin-14
CAS Number: 61950-59-2
Molecular Formula: C₇₆H₁₀₄N₁₈O₁₉S₂
Molecular Weight: 1536.774
Catalog: Research Areas Metabolic Disease
Create Date: 2016-08-22 16:00:07
Modify Date: 2024-01-07 11:07:06
(D-Trp8,D-Cys14)-Somatostatin-14 is a Somatostatin synthetic analogue. (D-Trp8,D-Cys14)-Somatostatin-14 can be used for the research of metabolic related diseases[1][2].

Name	(d-trp8,d-cys14)-somatostatin-14
Synonyms	1,2-Dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriaconta-5,8,11,17,20,23,26,29,32,35-decaene-4-carboxylic acid, 19,34-bis(4-aminobutyl)-6,9,12,18,21,24,27,30,33,36-decahydroxy-10-[(1R)-1-hydroxyethyl]-31-(2-hydroxy-2-iminoethyl)-7-(hydroxymethyl)-37-[[1-hydroxy-2-(methylamino)ethylidene]amino]-22-(1H-indol-3-ylmethyl)-15-oxo-13,25,28-tris(phenylmethyl)-, (4S,7S,8E,10S,13S,17E,19S,22R,25S,28S,31S,34S,35E,37R)- (4S,7S,8E,10S,13S,17E,19S,22R,25S,28S,31S,34S,35E,37R)-19,34-Bis(4-aminobutyl)-13,25,28-tribenzyl-6,9,12,18,21,24,27,30,33,36-decahydroxy-10-[(1R)-1-hydroxyethyl]-31-(2-hydroxy-2-iminoethyl)-7-(hydroxymethyl)-37-{[1-hydroxy-2-(methylamino)ethylidene]amino}-22-(1H-indol-3-ylmethyl)-15-oxo-1,2-dithia-5,8,11,14,17,20,23,26,29,32,35-undecaazacyclooctatriaconta-5,8,11,17,20,23,26,29,32,35-decaene-4-carboxylic acid

Description	(D-Trp8,D-Cys14)-Somatostatin-14 is a Somatostatin synthetic analogue. (D-Trp8,D-Cys14)-Somatostatin-14 can be used for the research of metabolic related diseases[1][2].
Related Catalog	Signaling Pathways >> Others >> Others Research Areas >> Metabolic Disease
In Vivo	(D-Trp8,D-Cys14)-Somatostatin-14 (12 μg/100g; i.p.) 不改变仓鼠肠道碳水化合物的体内吸收，但抑制雌性动物刷状缘乳糖酶活性[2]。
References	[1]. Vécsei L, et, al. Somatostatin and (D-Trp8, D-Cys14)-somatostatin delay extinction and reverse electroconvulsive shock induced amnesia in rats. Psychoneuroendocrinology. 1986;11(1):111-5. [2]. Martínez-Sapiña J, et, al. Somatostatin and its analogue (D-Trp8,D-Cys14)-somatostatin do not modify intestinal absorption in vivo of carbohydrates in hamster intestine, but they do modify some disaccharidases. Q J Exp Physiol. 1989 Nov;74(6):851-6.