77303-64-1

77303-64-1 structure
77303-64-1 structure
  • Name: Hydroxy-PEG4-methyl acetate
  • Chemical Name: methyl 14-hydroxy-3,6,9,12-tetraoxatetradecanoate
  • CAS Number: 77303-64-1
  • Molecular Formula: C11H22O7
  • Molecular Weight: 266.28800
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2016-06-08 04:54:31
  • Modify Date: 2024-01-15 06:15:00
  • Hydroxy-PEG4-methyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name methyl 14-hydroxy-3,6,9,12-tetraoxatetradecanoate
Description Hydroxy-PEG4-methyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula C11H22O7
Molecular Weight 266.28800
Exact Mass 266.13700
PSA 83.45000
Storage condition 2-8°C
Precursor  0

DownStream  1