Hydroxy-PEG4-methyl acetate

Modify Date: 2025-08-27 16:00:04

Hydroxy-PEG4-methyl acetate Structure
Hydroxy-PEG4-methyl acetate structure
Common Name Hydroxy-PEG4-methyl acetate
CAS Number 77303-64-1 Molecular Weight 266.28800
Density N/A Boiling Point N/A
Molecular Formula C11H22O7 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Hydroxy-PEG4-methyl acetate


Hydroxy-PEG4-methyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name methyl 14-hydroxy-3,6,9,12-tetraoxatetradecanoate

 Hydroxy-PEG4-methyl acetate Biological Activity

Description Hydroxy-PEG4-methyl acetate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C11H22O7
Molecular Weight 266.28800
Exact Mass 266.13700
PSA 83.45000
InChIKey CKNALYRJLYKSLK-UHFFFAOYSA-N
SMILES COC(=O)COCCOCCOCCOCCO
Storage condition 2-8°C

 Precursor & DownStream

Precursor  0

DownStream  1

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