- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: Obtusin
- Price: Check
- Purity: 97.0%
- Stocking Period: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Obtusin
- Price: ￥3528.0/20mg
- Purity: 98.0%
- Stocking Period: 2 Day
- Contact: Liu jia
- Email: 2130147988@qq.com
- DC Chemicals Limited
- China
- Product Name: 1,7-Dihydroxy-2,3,8-trimethoxy-6-methylanthracene-9,10-dione；Obtusin
- Price: $280.0/20mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 1,7-DIHYDROXY-2,3,8-TRIMETHOXY-6-METHYLANTHRACENE-9,10-DIONE
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
70588-05-5
70588-05-5 structure
- Name: Obtusin
- Chemical Name: Obtusin
- CAS Number: 70588-05-5
- Molecular Formula: C18H16O7
- Molecular Weight: 344.315
- Catalog: Signaling Pathways Neuronal Signaling Monoamine Oxidase
- Create Date: 2018-06-29 21:42:06
- Modify Date: 2025-08-22 23:48:09
-
Obtusin, isolated from Cassia obtusifolia Linn seed, is a highly selective and competitive human monoamine oxidase-A (hMAO-A) inhibitor with an IC50 of 11.12 μM and a Ki of 6.15. Obtusin plays a preventive role in neurodegenerative diseases, especially anxiety and depression[1].
| Name | Obtusin |
|---|---|
| Synonyms |
9,10-Anthracenedione, 1,7-dihydroxy-2,3,8-trimethoxy-6-methyl-
1,7-dihydroxy-2,3,8-trimethoxy-6-methylanthracene-9,10-dione 1,7-Dihydroxy-2,3,8-trimethoxy-6-methyl-9,10-anthraquinone |
| Description | Obtusin, isolated from Cassia obtusifolia Linn seed, is a highly selective and competitive human monoamine oxidase-A (hMAO-A) inhibitor with an IC50 of 11.12 μM and a Ki of 6.15. Obtusin plays a preventive role in neurodegenerative diseases, especially anxiety and depression[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: 11.12 μM (hMAO-A)[1] Ki: 6.15 (hMAO-A)[1] |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 614.9±55.0 °C at 760 mmHg |
| Molecular Formula | C18H16O7 |
| Molecular Weight | 344.315 |
| Flash Point | 227.0±25.0 °C |
| Exact Mass | 344.089600 |
| PSA | 102.29000 |
| LogP | 4.10 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.634 |
| Storage condition | 2-8℃ |
| HS Code | 2914690090 |
|---|
|
~71%
70588-05-5 |
| Literature: Cameron, Donald W.; Feutrill, Geoffrey I.; Gamble, Glenn B.; Stavrakis, John Tetrahedron Letters, 1986 , vol. 27, # 41 p. 4999 - 5002 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |
| HS Code | 2914690090 |
|---|---|
| Summary | 2914690090 other quinones。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |