Obtusin

Modify Date: 2025-08-22 23:48:09

Obtusin structure	Common Name	Obtusin
	CAS Number	70588-05-5	Molecular Weight	344.315
	Density	1.4±0.1 g/cm3	Boiling Point	614.9±55.0 °C at 760 mmHg
	Molecular Formula	C₁₈H₁₆O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	227.0±25.0 °C

Use of Obtusin

Obtusin, isolated from Cassia obtusifolia Linn seed, is a highly selective and competitive human monoamine oxidase-A (hMAO-A) inhibitor with an IC50 of 11.12 μM and a Ki of 6.15. Obtusin plays a preventive role in neurodegenerative diseases, especially anxiety and depression[1].

Name	Obtusin
Synonym	More Synonyms

Description	Obtusin, isolated from Cassia obtusifolia Linn seed, is a highly selective and competitive human monoamine oxidase-A (hMAO-A) inhibitor with an IC50 of 11.12 μM and a Ki of 6.15. Obtusin plays a preventive role in neurodegenerative diseases, especially anxiety and depression[1].
Related Catalog	Signaling Pathways >> Neuronal Signaling >> Monoamine Oxidase Research Areas >> Neurological Disease
Target	IC50: 11.12 μM (hMAO-A)[1] Ki: 6.15 (hMAO-A)[1]
References	[1]. Paudel P, et al. In Vitro and in Silico Human Monoamine Oxidase Inhibitory Potential of Anthraquinones, Naphthopyrones, and Naphthalenic Lactones from Cassia obtusifolia Linn Seeds. ACS Omega. 2019 Sep 18;4(14):16139-16152.

Density	1.4±0.1 g/cm3
Boiling Point	614.9±55.0 °C at 760 mmHg
Molecular Formula	C₁₈H₁₆O₇
Molecular Weight	344.315
Flash Point	227.0±25.0 °C
Exact Mass	344.089600
PSA	102.29000
LogP	4.10
Vapour Pressure	0.0±1.8 mmHg at 25°C
Index of Refraction	1.634
Storage condition	2-8℃

HS Code	2914690090

1-Methoxy-3-met...

CAS#:108637-73-6

5-hydroxy-6,7-d...

CAS#:108637-94-1

~71%

Obtusin

CAS#:70588-05-5

Literature: Cameron, Donald W.; Feutrill, Geoffrey I.; Gamble, Glenn B.; Stavrakis, John Tetrahedron Letters, 1986 , vol. 27, # 41 p. 4999 - 5002

Precursor 2
CAS#:108637-73-6 1-Methoxy-3-met... CAS#:108637-94-1 5-hydroxy-6,7-d...
DownStream 0

HS Code	2914690090
Summary	2914690090 other quinones。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%

9,10-Anthracenedione, 1,7-dihydroxy-2,3,8-trimethoxy-6-methyl-

1,7-dihydroxy-2,3,8-trimethoxy-6-methylanthracene-9,10-dione

1,7-Dihydroxy-2,3,8-trimethoxy-6-methyl-9,10-anthraquinone

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Obtusin
Price: Check
Purity: 97.0%
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Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Obtusin
Price: ￥3528.0/20mg
Purity: 98.0%
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DC Chemicals Limited
China
Product Name: 1,7-Dihydroxy-2,3,8-trimethoxy-6-methylanthracene-9,10-dione；Obtusin
Price: $280.0/20mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1,7-DIHYDROXY-2,3,8-TRIMETHOXY-6-METHYLANTHRACENE-9,10-DIONE
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Price: ￥6015/1g

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Obtusin

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.