- BioBioPha
- China
- Product Name: Tenuifolin
- Price: ￥Inquiry/20mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Xueping-Zheng
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: Tenuifolin
- Price: ￥788.0/20mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Liu jia
- DC Chemicals Limited
- China
- Product Name: Tenuifolin
- Price: $280.0/20mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 2β,27-Dihydroxy-3β-(β-D-glucopyranosyloxy)oleana-12-ene-23,28-dioic acid
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
20183-47-5
20183-47-5 structure
- Name: Tenuifolin
- Chemical Name: (2β,3β)-3-(β-D-Glucopyranosyloxy)-2,27-dihydroxyolean-12-ene-23,2 8-dioic acid
- CAS Number: 20183-47-5
- Molecular Formula: C36H56O12
- Molecular Weight: 680.823
- Catalog: Biochemical Plant extracts
- Create Date: 2018-08-12 16:42:33
- Modify Date: 2024-01-02 12:18:25
-
Tenuifolin is a triterpene isolated from Polygala tenuifolia Willd, has neuroprotective effects. Tenuifolin reduces Aβ secretion by inhibiting β-secretase. Tenuifolin improves learning and memory in aged mice by decreasing AChE activity and has the potential for Alzheimer’s disease (AD) treatment[1].
| Name | (2β,3β)-3-(β-D-Glucopyranosyloxy)-2,27-dihydroxyolean-12-ene-23,2 8-dioic acid |
|---|---|
| Synonyms |
(2β,3β)-3-(β-D-Glucopyranosyloxy)-2,27-dihydroxyolean-12-ene-24,28-dioic acid
Olean-12-ene-23,28-dioic acid, 3-(β-D-glucopyranosyloxy)-2,27-dihydroxy-, (2β,3β)- Tenuifolin Olean-12-ene-24,28-dioic acid, 3-(β-D-glucopyranosyloxy)-2,27-dihydroxy-, (2β,3β)- (2β,3β)-3-(β-D-Glucopyranosyloxy)-2,27-dihydroxyolean-12-ene-23,28-dioic acid |
| Description | Tenuifolin is a triterpene isolated from Polygala tenuifolia Willd, has neuroprotective effects. Tenuifolin reduces Aβ secretion by inhibiting β-secretase. Tenuifolin improves learning and memory in aged mice by decreasing AChE activity and has the potential for Alzheimer’s disease (AD) treatment[1]. |
|---|---|
| Related Catalog | |
| Target |
IC50: β-secretase; ACHE[1] |
| References |
| Density | 1.4±0.1 g/cm3 |
|---|---|
| Boiling Point | 853.6±65.0 °C at 760 mmHg |
| Melting Point | 201-204℃ |
| Molecular Formula | C36H56O12 |
| Molecular Weight | 680.823 |
| Flash Point | 262.2±27.8 °C |
| Exact Mass | 680.377197 |
| PSA | 214.44000 |
| LogP | 2.25 |
| Vapour Pressure | 0.0±0.6 mmHg at 25°C |
| Index of Refraction | 1.623 |
| Safety Phrases | 24/25 |
|---|---|
| HS Code | 29389090 |
|
~%
20183-47-5 |
| Literature: Chemical and Pharmaceutical Bulletin, , vol. 30, # 3 p. 810 - 821 |
|
~%
20183-47-5 |
| Literature: Chemical and Pharmaceutical Bulletin, , vol. 30, # 3 p. 810 - 821 |
| Precursor 2 | |
|---|---|
| DownStream 0 | |