Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 1-(ISOPROPYLAMINO)-3-(2-METHOXYPHENOXY)PROPAN-2-OL
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Purity: 98.0%
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5741-22-0

5741-22-0 structure

5741-22-0 structure

Name: 1-(ISOPROPYLAMINO)-3-(2-METHOXYPHENOXY)PROPAN-2-OL
Chemical Name: moprolol
CAS Number: 5741-22-0
Molecular Formula: C₁₃H₂₁NO₃
Molecular Weight: 239.31
Create Date: 2018-05-24 08:00:00
Modify Date: 2024-01-19 09:42:39
Moprolol ((±)-Moprolol) is an beta-adrenergic receptor blocker, which can be used for research in essential hypertension[1][2][3].

Name	moprolol

Description	Moprolol ((±)-Moprolol) is an beta-adrenergic receptor blocker, which can be used for research in essential hypertension[1][2][3].
Related Catalog	Research Areas >> Others Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor
Target	Beta-1 adrenergic receptor
In Vitro	l-Moprolol 是一种 β 阻断剂的 l-对映体，具有低负性肌力活性和轻度内在拟交感神经活性，可有效用于全身性高血压研究。在原发性开角型青光眼 (POAG) 或高眼压 (OHT) 模型中，局部应用l-Moprolol 可与噻洛尔一样有效地降低眼压 (IOP)，由于其对支气管肌肉缺乏活性，已成为抑制青光眼的一种很有前景的化合物[3]。
References	[1]. Borowiecki P, et al. Development of a novel chemoenzymatic route to enantiomerically enriched β-adrenolytic agents. A case study toward propranolol, alprenolol, pindolol, carazolol, moprolol, and metoprolol. RSC Adv. 2022 Aug 10;12(34):22150-22160. [2]. Liu J, et al. beta1-Adrenergic receptor polymorphisms influence the response to metoprolol monotherapy in patients with essential hypertension. Clin Pharmacol Ther. 2006 Jul;80(1):23-32. [3]. Rossetti L, et al. The efficacy of the combination of l-moprolol and dipivefrin in reducing the intraocular pressure in primary open-angle glaucoma or in ocular hypertension. Graefes Arch Clin Exp Ophthalmol. 1994 Nov;232(11):670-4.

Density	1.054g/cm3
Boiling Point	379.2ºC at 760mmHg
Molecular Formula	C₁₃H₂₁NO₃
Molecular Weight	239.31
Flash Point	183.2ºC
Exact Mass	239.15200
PSA	50.72000
LogP	1.82380
Index of Refraction	1.509

25772-81-0 structure

25772-81-0

75-31-0 structure

75-31-0

~%

5741-22-0 structure

5741-22-0

Literature: Journal of Medicinal Chemistry, , vol. 12, # 4 p. 638 - 642

Precursor 1
75-31-0
DownStream 0