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7558-80-7

7558-80-7 structure
7558-80-7 structure
  • Name: sodium dihydrogenphosphate
  • Chemical Name: sodium dihydrogenphosphate
  • CAS Number: 7558-80-7
  • Molecular Formula: H2NaO4P
  • Molecular Weight: 119.98
  • Catalog: Inorganic chemical industry Inorganic salt Phosphides, metal phosphoric acid, metaphosphoric acid, hypophosphorous acid and pyrophosphate
  • Create Date: 2018-02-06 08:00:00
  • Modify Date: 2026-06-30 16:48:09
  • Dihydrogen monosodium phosphate (NaH2PO4, NDHP) is a chemical compound of sodium with a phosphate counter ion. Sorbitan monooleate, in combination with other sodium phosphates, can serve a pH buffer. Dihydrogen monosodium phosphate can be used as an excipient, such as buffer, chelating agent. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].
Name sodium dihydrogenphosphate
Synonyms primysodiumphosphate
NATRIUMDIHYDROGENPHOSPHATE
SODIUMPHOSPHATEMONOBASIC,ANHYDROUS,FCC(BULK
Sodium dihydrogenorthophosphate
Phosphoric acid dihydrogen sodium salt
SODIUM PHOSPHATE MONOBASIC BIOXTRA
SODIUM PHOSPHATE, MONOBASIC ANHYDROUS
KL FISCHER TITRANT 5
MSP Sodium phosphate monobasic Monosodium phosphate Sodium dihydrogen phosphate
phosphatemonobasiquedesodium
SODIUM PHOSPHATE MONOBASIC ANHYDROUS
Sodium dihydngen phoshate anhydrous
MFCD04113752
Monosodium phosphate
SODIUM DIHYDROGEN PHOSPHATE-16O4
sodiumorthophosphate,primy
Sodium phosphate monobasic
monosorbxp-4
Chebi
MONO SODIUM PHOSPHATE, INDUSTRIAL ADE
MONO SODIUM PHOSPHATE, FOOD ADE
Sodium dihydrogen phosphate, anhydrous, ade
2-MERCAPTOETHANOL BIOTECHNOLOGY ADE
MONOSODIUM PHOSPHATE (MSP)
sodiumphosphate(na(h2po4))
Monosodium dihydrogen phosphate
sodiumdihydrogenphosphate(nah2po4)
Sodium dihydrogen phosphate anhydrous
MONOSODIUMPHOSPHATE(BULK
sodiumdihydrogenphosphateanhydrous
Sodium dihydrogen phosphate solution
SODIUMDIHYDROPHOSPHATE
SODIUMMONOBASIHOSPHATE
acidsodiumphosphate
Sodium phosphate, monobasic, anhydrous, for analysis
monosodiumphosphate(sodiumdihydrogen
Sodium phosphate monobasic Bioreagent, for moleculbiology
SODIUM PHOSPHATE MONOBASIC ANHYDROUS POWDER
Sodium dihydrogen (16O4)phosphate
sodiumbiphosphateanhydrous
Sodium phosphate monobasic, anhydrousReagent, (Titration)
Sodium hydrogen phosphate，Dried
Sodiumdihydrogenphosphate,an
SODIUM THIOSULFATE 5H2O HIGH PURITY
sodiummonobasihosphate(nah2po4)
Sodium dihydrogen phosphate anhydrous 99.99 Suprapur
monosodiumhydrogenphosphate
MONOBASICSODIUMPHOSPHATE,ANHYDROUS
Sodium phosphate, monobasic,for analysis,anhydrous
monosodiumdihydrogenorthophosphate
SODIUMSALTSOFORTHOPHOSPHORICACID
EINECS 231-449-2
Sodium dihydrogen phosphate
SODIUM PHOSPHATE MONOBASIC, REAGENTP
monosodiumphosphate(sodiumdihydrogenphosphate)
sodiumdihydrogenmonophosphate
PBS, 10X Solution, pH 7.4
MONOSODIUMMONOPHOSPHATE
sodiumprimyphosphate
SODIUM PHOSPHATE MONOBASIC, ANHYDROU
Phosphoricacid,monosodiumsalt
sodiumdihydrogenphosphate(1:2:1)
Description Dihydrogen monosodium phosphate (NaH2PO4, NDHP) is a chemical compound of sodium with a phosphate counter ion. Sorbitan monooleate, in combination with other sodium phosphates, can serve a pH buffer. Dihydrogen monosodium phosphate can be used as an excipient, such as buffer, chelating agent. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2].
Related Catalog
References

[1]. Kumar H, et al. Investigations on solute–solvent interactions of amino acids in aqueous solutions of sodium dihydrogen phosphate at different temperatures[J]. Monatshefte für Chemie-Chemical Monthly, 2014, 145: 1063-1082.

[2]. Elder DP, et al. Pharmaceutical excipients - quality, regulatory and biopharmaceutical considerations. Eur J Pharm Sci. 2016 May 25;87:88-99.  

Density 1.40 g/mL at 20 °C
Boiling Point 100°C
Melting Point <0ºC
Molecular Formula H2NaO4P
Molecular Weight 119.98
Exact Mass 119.958839
PSA 90.40000
Storage condition Store at RT.
Stability Stable. Incompatible with heavy metals, strong acids.
Water Solubility H2O: 5 M, clear, colorless

CHEMICAL IDENTIFICATION

RTECS NUMBER :
WA1900000
CAS REGISTRY NUMBER :
7558-80-7
LAST UPDATED :
199701
DATA ITEMS CITED :
8
MOLECULAR FORMULA :
H2-O4-P.Na
MOLECULAR WEIGHT :
119.98
WISWESSER LINE NOTATION :
NA P-O2-Q2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Human
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 9,349,1959
TYPE OF TEST :
Standard Draize test
ROUTE OF EXPOSURE :
Administration into the eye
SPECIES OBSERVED :
Rodent - rabbit
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 9,349,1959 ** ACUTE TOXICITY DATA **
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
8290 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
28ZPAK "Sbornik Vysledku Toxixologickeho Vysetreni Latek A Pripravku," Marhold, J.V., Institut Pro Vychovu Vedoucicn Pracovniku Chemickeho Prumyclu Praha, Czechoslovakia, 1972 Volume(issue)/page/year: -,16,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
250 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
EMSUA8 Experimental Medicine and Surgery. (Brooklyn, NY) V.1-29, 1943-71. Suspended. Volume(issue)/page/year: 4,223,1946 *** U.S. STANDARDS AND REGULATIONS *** EPA FIFRA 1988 PESTICIDE SUBJECT TO REGISTRATION OR RE-REGISTRATION FEREAC Federal Register. (U.S. Government Printing Office, Supt. of Documents, Washington, DC 20402) V.1- 1936- Volume(issue)/page/year: 54,7740,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83818 No. of Facilities: 9820 (estimated) No. of Industries: 107 No. of Occupations: 77 No. of Employees: 49018 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83818 No. of Facilities: 13232 (estimated) No. of Industries: 123 No. of Occupations: 104 No. of Employees: 289281 (estimated) No. of Female Employees: 145939 (estimated)
Personal Protective Equipment Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases R36/37/38
Safety Phrases S26-S36
RIDADR NONH for all modes of transport
WGK Germany 1
RTECS WA1900000
HS Code 2835220000
HS Code 2835220000
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