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14636-12-5

14636-12-5 structure
14636-12-5 structure
  • Name: Terlipressin acetate salt
  • Chemical Name: Terlipressin
  • CAS Number: 14636-12-5
  • Molecular Formula: C52H74N16O15S2
  • Molecular Weight: 1227.372
  • Catalog: API Urinary system medication Diabetes insipidus medication
  • Create Date: 2018-06-15 22:34:56
  • Modify Date: 2024-01-02 08:31:31
  • Terlipressin is a potent vasoconstrictor that acts via V1 receptors on arteriolar smooth muscle cells. Terlipressin can result in splanchnic vasoconstriction augmenting systemic arterial blood pressure with beneficial circulatory and renal effects that would be expected to also ameliorate the key pathophysiological changes responsible for the development of refractory ascites

Name Terlipressin
Synonyms (2S)-1-{[(4R,7S,10S,13S,16S,19R)-19-{[({[(Aminoacetyl)amino]acetyl}amino)acetyl]amino}-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-N-{(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxohexan-2-yl}pyrrolidine-2-carboxamide (non-preferred name)
Terlipressin
EINECS 238-680-8
MFCD00155450
(2S)-1-{[(4R,7S,10S,13S,16S,19R)-19-{[({[(Aminoacetyl)amino]acetyl}amino)acetyl]amino}-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-(4-hydroxybenzyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl]carbonyl}-N-{(2S)-6-amino-1-[(2-amino-2-oxoethyl)amino]-1-oxo-2-hexanyl}-2-pyrrolidinecarboxamide
N-(N-(N-Glycylglycyl)glycyl)-8-L-lysinevasopressin
Terlipressin Acetate
Description Terlipressin is a potent vasoconstrictor that acts via V1 receptors on arteriolar smooth muscle cells. Terlipressin can result in splanchnic vasoconstriction augmenting systemic arterial blood pressure with beneficial circulatory and renal effects that would be expected to also ameliorate the key pathophysiological changes responsible for the development of refractory ascites
Related Catalog
References

[1]. Jao YT et al. Refractory torsade de pointes induced by terlipressin (Glypressin). Int J Cardiol, 2016 Jul 30, 222:135-140.

Density 1.5±0.1 g/cm3
Boiling Point 1824.0±65.0 °C at 760 mmHg
Molecular Formula C52H74N16O15S2
Molecular Weight 1227.372
Flash Point 1056.9±34.3 °C
Exact Mass 1226.496094
PSA 563.45000
LogP -6.75
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.664
Storage condition -20°C
Precursor  0

DownStream  3