19275-46-8
19275-46-8 structure
- Name: 5,9-Dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-buten-1-yl)-3,4-dihydro-2H,6H-pyrano[3,2-b]xanthen-6-one
- Chemical Name: 3-isomangostin
- CAS Number: 19275-46-8
- Molecular Formula: C24H26O6
- Molecular Weight: 410.460
- Catalog: Research Areas Cancer
- Create Date: 2018-12-26 14:57:05
- Modify Date: 2024-01-02 11:11:59
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3-Isomangostin, extracted from Garciniamangostana.L. shell, is a potent MutT homologue 1 (MTH1) inhibitor with an IC50 value of 52 nM. 3-isomangostin would be an attractive chemical tool for the development of anticancer agents[1].
| Name | 3-isomangostin |
|---|---|
| Synonyms |
5,9-Dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-buten-1-yl)-3,4-dihydro-2H,6H-pyrano[3,2-b]xanthen-6-one
5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-but-2-enyl)-3,4-dihydro-2H-pyrano[3,2-b]xanthen-6-one 2H,6H-Pyrano[3,2-b]xanthen-6-one, 3,4-dihydro-5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-buten-1-yl)- 9-hydroxycalabaxanthone 3,4-Dihydro-5,9-dihydroxy-8-methoxy-2,2-dimethyl-7-(3-methyl-2-butenyl)-2H,6H-pyrano[3,2-b]xanthen-6-one |
| Description | 3-Isomangostin, extracted from Garciniamangostana.L. shell, is a potent MutT homologue 1 (MTH1) inhibitor with an IC50 value of 52 nM. 3-isomangostin would be an attractive chemical tool for the development of anticancer agents[1]. |
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| Related Catalog | |
| References |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 615.9±55.0 °C at 760 mmHg |
| Melting Point | 155-160ºC |
| Molecular Formula | C24H26O6 |
| Molecular Weight | 410.460 |
| Flash Point | 212.3±25.0 °C |
| Exact Mass | 410.172943 |
| PSA | 89.13000 |
| LogP | 5.72 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.605 |
|
~50%
19275-46-8 |
| Literature: Australian Journal of Chemistry, , vol. 51, # 3 p. 249 - 254 |
|
~%
19275-46-8 |
| Literature: Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 26, # 1-12 p. 281 - 282 |
| Precursor 1 | |
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| DownStream 0 | |