141626-36-0

141626-36-0 structure

Name: Dronedarone
Chemical Name: dronedarone
CAS Number: 141626-36-0
Molecular Formula: C₃₁H₄₄N₂O₅S
Molecular Weight: 556.756
Catalog: API Circulatory system medication Antiarrhythmic drug
Create Date: 2018-05-25 08:00:00
Modify Date: 2024-01-02 16:37:33
Dronedarone(Multaq) is a newer therapeutic agent with a structural resemblance to amiodarone and a better side effect profile; it is a multichannel blocker with antiadrenergic properties and has been evaluated in both rate and rhythm control strategies in the management of AF.IC50 value:Target: multichannel blocker

Name	dronedarone
Synonyms	UNII-JQZ1L091Y2 N-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-1-benzofuran-5-yl]methanesulfonamide Multaq N-(2-Butyl-3-(4-(3-(dibutylamino)propoxy)benzoyl)-1-benzofuran-5-yl)methanesulfonamide Methanesulfonamide, N-[2-butyl-3-[4-[3-(dibutylamino)propoxy]benzoyl]-5-benzofuranyl]- Dronedarone N-(2-Butyl-3-{4-[3-(dibutylamino)propoxy]benzoyl}-1-benzofuran-5-yl)methanesulfonamide

Description	Dronedarone(Multaq) is a newer therapeutic agent with a structural resemblance to amiodarone and a better side effect profile; it is a multichannel blocker with antiadrenergic properties and has been evaluated in both rate and rhythm control strategies in the management of AF.IC50 value:Target: multichannel blocker
Related Catalog	Signaling Pathways >> Autophagy >> Autophagy Signaling Pathways >> GPCR/G Protein >> mAChR Signaling Pathways >> Neuronal Signaling >> mAChR Research Areas >> Cardiovascular Disease
References	[1]. Piccinni C, et al.Trends in antiarrhythmic drug use after marketing authorization of dronedarone: comparison between Emilia Romagna (Italy) and Sweden.Eur J Clin Pharmacol. 2012 Sep 1. [2]. Benaim G, et al.The emerging role of amiodarone and dronedarone in Chagas disease.Nat Rev Cardiol. 2012 Aug 7. [3]. Rosman J, et al. Possible Proarrhythmia with Dronedarone.J Cardiovasc Electrophysiol. 2012 Jul 19. [4]. Kao DP, et al. Proarrhythmic Potential of Dronedarone: Emerging Evidence from Spontaneous Adverse Event Reporting.Pharmacotherapy. 2012 Jun 28. [5]. Manakshe G, Rao BH.Dronedarone-current status in management of atrial fibrillation.Indian Heart J. 2012 Mar-Apr;64(2):182-6. Epub 2012 Apr 28.

Hazard Codes	Xi
HS Code	3004909090

Precursor 3
111-92-2 1912-32-9 627040-50-0
DownStream 0

HS Code	3004909090