163490-78-6
163490-78-6 structure
- Name: hnNOS-IN-3
- Chemical Name: etpi hcl
- CAS Number: 163490-78-6
- Molecular Formula: C10H12ClF3N2S
- Molecular Weight: 284.73
- Catalog: Signaling Pathways Immunology/Inflammation NO Synthase
- Create Date: 2018-12-28 15:31:40
- Modify Date: 2025-08-27 00:40:12
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hnNOS-IN-3 (compound 39) is a selective nNOS inhibitor, with a Ki of 0.32 μM. The nNOS binding of hnNOS-IN-3 is competitive with L-arginine. The selectivity of hnNOS-IN-3 for nNOS versus iNOS (Ki=37 μM) and eNOS (Ki=9.4 μM) is 115-fold and 29-fold, respectively[1].
| Name | etpi hcl |
|---|---|
| Synonyms |
Carbamimidothioic acid, N'-[4-(trifluoromethyl)phenyl]-, ethyl ester, hydrochloride (1:1)
TFPI HCL EPIT HCL MFCD01320531 Ethyl N'-[4-(trifluoromethyl)phenyl]carbamimidothioate hydrochloride (1:1) TFPI hydrochloride SEPIT HCL ETPI,HYDROCHLORIDE |
| Description | hnNOS-IN-3 (compound 39) is a selective nNOS inhibitor, with a Ki of 0.32 μM. The nNOS binding of hnNOS-IN-3 is competitive with L-arginine. The selectivity of hnNOS-IN-3 for nNOS versus iNOS (Ki=37 μM) and eNOS (Ki=9.4 μM) is 115-fold and 29-fold, respectively[1]. |
|---|---|
| Related Catalog | |
| Target |
nNOS:0.32 μM (Ki) eNOS:9.4 μM (Ki) iNOS:37 μM (Ki) |
| References |
| Density | 1.27 g/cm3 |
|---|---|
| Boiling Point | 322.3ºC at 760 mmHg |
| Melting Point | 143-147ºC |
| Molecular Formula | C10H12ClF3N2S |
| Molecular Weight | 284.73 |
| Flash Point | 148.8ºC |
| Exact Mass | 284.036194 |
| PSA | 61.18000 |
| LogP | 4.77990 |
| Vapour Pressure | 0.000281mmHg at 25°C |
| Safety Phrases | S24/25 |
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