4546-54-7

4546-54-7 structure

Name: 2-amino-9-(β-D-ribofuranosyl)purine
Chemical Name: 2-Aminopurine Riboside
CAS Number: 4546-54-7
Molecular Formula: C₁₀H₁₃N₅O₄
Molecular Weight: 267.24
Catalog: Biochemical Nucleoside drugs Nucleoside intermediate
Create Date: 2018-07-01 12:37:11
Modify Date: 2024-01-07 20:14:45
(2R,3R,4S,5R)-2-(2-amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (9-pentofuranosyl-9H-purin-2-amine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2-Aminopurine Riboside
Synonyms	9H-purine, 2-amino-9-β-d-ribofuranosyl-, 9-(β-D-Ribofuranosyl)-9H-purin-2-amine 9H-Purin-2-amine, 9-β-D-ribofuranosyl- 2-amino-9-(β-D-ribofuranosyl)purine 9H-Purine, 2-amino-9-β-D-ribofuranosyl- 2-(2-aminopurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol

Description	(2R,3R,4S,5R)-2-(2-amino-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol (9-pentofuranosyl-9H-purin-2-amine) is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

HS Code	2933599090

HS Code	2933599090
Summary	2933599090. other compounds containing a pyrimidine ring (whether or not hydrogenated) or piperazine ring in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%