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  • Product Name: Bicyclomycin
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38129-37-2

38129-37-2 structure
38129-37-2 structure
  • Name: Bicyclomycin
  • Chemical Name: bicozamycin
  • CAS Number: 38129-37-2
  • Molecular Formula: C12H18N2O7
  • Molecular Weight: 302.28
  • Catalog: Signaling Pathways Anti-infection Bacterial
  • Create Date: 2018-06-17 20:19:42
  • Modify Date: 2024-01-02 18:04:29
  • Bicyclomycin is an antibiotic. Bicyclomycin has anti-Bacterial activity against Gram-negative bacteria except Proteus and Pseudomonas aeruginosa[1].

Name bicozamycin
Synonyms antibiotic WS-4545
bicyclomycin
WS-4545
(1S)-6-hydroxy-5-methylene-1-((1S,2S)-1,2,3-trihydroxy-2-methyl-propyl)-2-oxa-7,9-diaza-bicyclo[4.2.2]decane-8,10-dione
BicozaMycin benzoate
Description Bicyclomycin is an antibiotic. Bicyclomycin has anti-Bacterial activity against Gram-negative bacteria except Proteus and Pseudomonas aeruginosa[1].
Related Catalog
References

[1]. NISHIDA, M., et al. BICYCLOMYCIN, A NEW ANTIBIOTIC. The Journal of Antibiotics, 25(10), 582–593.

Density 1.57g/cm3
Boiling Point 786.6ºC at 760 mmHg
Molecular Formula C12H18N2O7
Molecular Weight 302.28
Flash Point 429.5ºC
Exact Mass 302.11100
PSA 148.35000
Index of Refraction 1.632

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DT7470000
CHEMICAL NAME :
Bicyclomycin
CAS REGISTRY NUMBER :
38129-37-2
LAST UPDATED :
199309
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C12-H18-N2-O7
MOLECULAR WEIGHT :
302.32

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>4 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 25,569,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 4(1),235,1980
TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>4 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 25,569,1972
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
3 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 4(1),235,1980