Bicyclomycin

Modify Date: 2025-08-26 09:09:14

Bicyclomycin structure	Common Name	Bicyclomycin
	CAS Number	38129-37-2	Molecular Weight	302.28
	Density	1.57g/cm3	Boiling Point	786.6ºC at 760 mmHg
	Molecular Formula	C₁₂H₁₈N₂O₇	Melting Point	N/A
	MSDS	N/A	Flash Point	429.5ºC

Use of Bicyclomycin

Bicyclomycin is an antibiotic. Bicyclomycin has anti-Bacterial activity against Gram-negative bacteria except Proteus and Pseudomonas aeruginosa[1].

Name	bicozamycin
Synonym	More Synonyms

Description	Bicyclomycin is an antibiotic. Bicyclomycin has anti-Bacterial activity against Gram-negative bacteria except Proteus and Pseudomonas aeruginosa[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. NISHIDA, M., et al. BICYCLOMYCIN, A NEW ANTIBIOTIC. The Journal of Antibiotics, 25(10), 582–593.

Density	1.57g/cm3
Boiling Point	786.6ºC at 760 mmHg
Molecular Formula	C₁₂H₁₈N₂O₇
Molecular Weight	302.28
Flash Point	429.5ºC
Exact Mass	302.11100
PSA	148.35000
Index of Refraction	1.632
InChIKey	WOUDXEYYJPOSNE-DSRXWYFFSA-N
SMILES	C=C1CCOC2(C(O)C(C)(O)CO)NC(=O)C1(O)NC2=O

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DT7470000

CHEMICAL NAME :: Bicyclomycin

CAS REGISTRY NUMBER :: 38129-37-2

LAST UPDATED :: 199309

DATA ITEMS CITED :: 4

MOLECULAR FORMULA :: C12-H18-N2-O7

MOLECULAR WEIGHT :: 302.32

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 25,569,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 5 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 4(1),235,1980

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: >4 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 25,569,1972

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 3 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: 85GDA2 "CRC Handbook of Antibiotic Compounds," Vols.1- , Berdy, J., Boca Raton, FL, CRC Press, 1980- Volume(issue)/page/year: 4(1),235,1980

Precursor 0
DownStream 4
CAS#:114533-59-4 4-hydroxy-3-(2-... CAS#:114533-60-7 3,4-dihydroxy-5... CAS#:37134-40-0 Bicyclomycin be... CAS#:41238-48-6 1-hydroxy-2-met...

Name: Minimum inhibitory concentration against Bacillus sp. TA
Source: ChEMBL
Target: Bacillus
External Id: CHEMBL875043

Name: Minimum inhibitory concentration against yeast Candida albicans 155
Source: ChEMBL
Target: Candida albicans
External Id: CHEMBL661404

Name: Minimum inhibitory concentration against Bacillus sp. E
Source: ChEMBL
Target: Bacillus
External Id: CHEMBL652688

Name: Minimum inhibitory concentration against Klebsiella pneumoniae 369
Source: ChEMBL
Target: Klebsiella pneumoniae
External Id: CHEMBL700978

Name: Minimum inhibitory concentration against Paecilomyces varioti M16
Source: ChEMBL
Target: Paecilomyces variotii
External Id: CHEMBL760687

Name: Minimum inhibitory concentration against Acinetobacter calcoaceticus PCl3
Source: ChEMBL
Target: Acinetobacter calcoaceticus
External Id: CHEMBL636116

Name: Minimum inhibitory concentration against Streptococcus faecium ATCC 8043
Source: ChEMBL
Target: Enterococcus faecium
External Id: CHEMBL811314

Name: Minimum inhibitory concentration against Mycobacterium phlei 78
Source: ChEMBL
Target: Mycolicibacterium phlei
External Id: CHEMBL751646

Name: Minimum inhibitory concentration against Staphylococcus aureus 82
Source: ChEMBL
Target: Staphylococcus aureus
External Id: CHEMBL808832

Name: Minimum inhibitory concentration against Bacillus subtilis 558
Source: ChEMBL
Target: Bacillus subtilis
External Id: CHEMBL650445

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antibiotic WS-4545

bicyclomycin

WS-4545

(1S)-6-hydroxy-5-methylene-1-((1S,2S)-1,2,3-trihydroxy-2-methyl-propyl)-2-oxa-7,9-diaza-bicyclo[4.2.2]decane-8,10-dione

BicozaMycin benzoate

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Shanghai Nianxing Industrial Co., Ltd
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Product Name: Bicyclomycin
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Bicyclomycin

Use of Bicyclomycin

Names

Bicyclomycin Biological Activity

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Precursor & DownStream

BicyclomycinBioassay

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.