67005-97-4
67005-97-4 structure
- Name: Adenosine,N-2-propynyl- (9CI)
- Chemical Name: 2-(hydroxymethyl)-5-[6-(prop-2-ynylamino)purin-9-yl]oxolane-3,4-diol
- CAS Number: 67005-97-4
- Molecular Formula: C13H15N5O4
- Molecular Weight: 305.29
- Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
- Create Date: 2016-04-02 05:13:14
- Modify Date: 2024-01-20 23:47:55
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N-Propargyladenosine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1].
| Name | 2-(hydroxymethyl)-5-[6-(prop-2-ynylamino)purin-9-yl]oxolane-3,4-diol |
|---|---|
| Synonyms |
6-propargyl-adenosine
N6-prop-2-ynyl-adenosine N6-Propynyladenosine N6-propargyladenosine |
| Description | N-Propargyladenosine is an adenosine analogue. Adenosine analogs mostly act as smooth muscle vasodilators and have also been shown to inhibit cancer progression. The popular products in this series are adenosine phosphate, Acadesine (HY-13417), Clofarabine (HY-A0005), Fludarabine phosphate (HY-B0028) and Vidarabine (HY-B0277)[1]. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.66g/cm3 |
|---|---|
| Boiling Point | 679.4ºC at 760 mmHg |
| Molecular Formula | C13H15N5O4 |
| Molecular Weight | 305.29 |
| Flash Point | 364.7ºC |
| Exact Mass | 305.11200 |
| PSA | 125.55000 |
| Index of Refraction | 1.749 |
|
~61%
67005-97-4 |
| Literature: Carter-O'Connell, Ian; Jin, Haihong; Morgan, Rory K.; David, Larry L.; Cohen, Michael S. Journal of the American Chemical Society, 2014 , vol. 136, # 14 p. 5201 - 5204 |
|
~%
67005-97-4 |
| Literature: Tararov, Vitali I.; Kolyachkina, Svetlana V.; Alexeev, Cyril S.; Mikhailov, Sergey N. Synthesis, 2011 , # 15 p. 2483 - 2489 |
|
~46%
67005-97-4 |
| Literature: Fleysher; Bernacki; Bullard Journal of medicinal chemistry, 1980 , vol. 23, # 12 p. 1448 - 1452 |
|
~%
67005-97-4 |
| Literature: Tararov, Vitali I.; Kolyachkina, Svetlana V.; Alexeev, Cyril S.; Mikhailov, Sergey N. Synthesis, 2011 , # 15 p. 2483 - 2489 |
|
~%
67005-97-4 |
| Literature: Tararov, Vitali I.; Kolyachkina, Svetlana V.; Alexeev, Cyril S.; Mikhailov, Sergey N. Synthesis, 2011 , # 15 p. 2483 - 2489 |
