134742-26-0

134742-26-0 structure

Name: NSC639828
Chemical Name: 2-amino-N-[[4-(5-bromopyrimidin-2-yl)oxy-3-chlorophenyl]carbamoyl]benzamide
CAS Number: 134742-26-0
Molecular Formula: C₁₈H₁₃BrClN₅O₃
Molecular Weight: 462.68500
Catalog: Research Areas Cancer
Create Date: 2017-09-17 22:16:06
Modify Date: 2024-01-09 18:28:40
NSC639828 is a potent inhibitor of DNA polymerase with an IC50 of 70 μM. NSC639828 has high antitumor activity. NSC639828 has the potential for the treatment of cancer disease[1].

Name	2-amino-N-[[4-(5-bromopyrimidin-2-yl)oxy-3-chlorophenyl]carbamoyl]benzamide

Description	NSC639828 is a potent inhibitor of DNA polymerase with an IC50 of 70 μM. NSC639828 has high antitumor activity. NSC639828 has the potential for the treatment of cancer disease[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Others >> Others
Target	DNA polymerase[1].
References	[1]. Abdel-Aziz W, et al. Effect of novel benzoylphenylurea derivatives on DNA polymerase alpha activity using the synthesome-based in vitro model system. Invest New Drugs. 2003;21(4):421-428.