NSC639828

Modify Date: 2025-08-26 23:29:12

NSC639828 Structure
NSC639828 structure
Common Name NSC639828
CAS Number 134742-26-0 Molecular Weight 462.68500
Density 1.663g/cm3 Boiling Point N/A
Molecular Formula C18H13BrClN5O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NSC639828


NSC639828 is a potent inhibitor of DNA polymerase with an IC50 of 70 μM. NSC639828 has high antitumor activity. NSC639828 has the potential for the treatment of cancer disease[1].

 Names

Name 2-amino-N-[[4-(5-bromopyrimidin-2-yl)oxy-3-chlorophenyl]carbamoyl]benzamide

 NSC639828 Biological Activity

Description NSC639828 is a potent inhibitor of DNA polymerase with an IC50 of 70 μM. NSC639828 has high antitumor activity. NSC639828 has the potential for the treatment of cancer disease[1].
Related Catalog
Target

DNA polymerase[1].

References

[1]. Abdel-Aziz W, et al. Effect of novel benzoylphenylurea derivatives on DNA polymerase alpha activity using the synthesome-based in vitro model system. Invest New Drugs. 2003;21(4):421-428.

 Chemical & Physical Properties

Density 1.663g/cm3
Molecular Formula C18H13BrClN5O3
Molecular Weight 462.68500
Exact Mass 460.98900
PSA 119.23000
LogP 5.27400
Index of Refraction 1.708
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